PLA2G2A fuels gallbladder cancer stemness and immune suppression
A new Cellular Oncology study shows that the enzyme PLA2G2A drives gallbladder cancer progression by promoting cancer stemness through PLA2R1, ...
Tag: cancer stemness
Natural Saponin Esculentoside A Curbs Liver Cancer Growth by Stabilizing RORB Protein
A new preclinical study reports that the plant-derived saponin esculentoside A suppresses hepatocellular carcinoma growth and stemness in cells and ...
Plant-Derived Nanoparticles Restore Tumor-Suppressor miR-34a to Block NOTCH1 in Triple-Negative Breast Cancer
Folate-functionalized chitosan nanoparticles carrying an Ailanthus excelsa stembark extract restored miR-34a and suppressed NOTCH1 signaling, reducing tumor growth, metastasis and ...
Rising Cancer Stemness Drives Prostate Cancer Progression and Treatment Resistance
A large integrated transcriptomic study shows that rising cancer stemness tracks prostate cancer progression, lineage plasticity, therapy resistance, and poor ...
R-Loop Gene Signature Predicts Survival and Immune Landscape in Esophageal Cancer
Researchers have built the first R-loop-related gene signature for esophageal squamous cell carcinoma, identifying BRIX1, CHEK1, and NUP155 as core ...
Lost tumor brake found to rewire liver cancer cell power plants
Researchers report that loss of the tumor suppressor LZTR1 stabilizes mitochondrial transcription factor A, reprogramming liver cancer cells toward complex ...
CircKIAA1617 Enhances Stemness in ER-Positive Breast Cancer
In a groundbreaking study published in Molecular Cancer, researchers explored the role of CircKIAA1617 in the context of estrogen receptor-positive ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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