Tumors Are Not Sterile: How Microbes Living Inside Cancers Reshape Immunity and Immunotherapy
A new review in Molecular Cancer argues that microbes living inside tumors dynamically reprogram immunity and can determine whether patients ...
Tag: Cancer immunology
Immune Cells Feed Breast Cancer Tumors as AI and DNA Testing Reshape Cancer Care
New MSK studies reveal that immune cells secretly feed triple-negative breast cancer, a CXCR2 blocker sensitizes leptomeningeal metastases to radiation, ...
How aging and sex reshape the immune system’s fight against cancer
A new Nature Aging study from Mass General Brigham shows that male and female immune systems age differently, with earlier ...
Shrinking Lymph Nodes Explain Why Men Lose Cancer-Fighting T Cells Earlier
A Nature Aging study shows that earlier thymic involution and accelerated conversion of naive CD8+ T cells into short-lived virtual ...
SPP1 emerges as a master switch shaping the tumor immune landscape
A new review details how the matrix protein SPP1 orchestrates immunosuppression across the tumor microenvironment and outlines emerging strategies to ...
Immune Booster Cells Show Promise After Checkpoint Blockers in Liver Cancer
A Taiwanese preliminary study found that following a short course of immune checkpoint inhibitors with infusions of tumor-primed dendritic cells ...
Gamma Delta T Cells Blur the Line Between Innate and Adaptive Immunity
New research in Nature shows that gamma delta T cells rely on their adaptive T cell receptors in real time ...
Inside Tumors’ Hidden Immune Hubs: Spatial Maps Reveal Zoned Architecture of Tertiary Lymphoid Structures
A new spatial transcriptomics study shows that tertiary lymphoid structures in tumors are spatially zoned immune organs whose core-periphery organization ...
Blood Cell DNA Fingerprints Could Expose Hidden Inflammation in Diseased Tissue
Researchers have identified DNA methylation markers unique to white blood cells that can quantify immune infiltration in saliva, inflammatory disease ...
Scientists Uncover Why a Key Antitumor T Cell Loses Its Fight in Ovarian Cancer
A new study links CEACAM1 expression and dysregulated SHP-1, LCK, and ZAP70 signaling to the functional exhaustion of follicular cytotoxic ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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