Tag: cancer immunology research

Johns Hopkins researchers measured the metabolism of immune cells inside human head and neck tumors and found that exhausted T ...

Researchers engineered an anti-C4d antibody that targets complement fragments left on tumor cells that survived antibody therapy, boosting complement-mediated killing ...

A phase II pilot trial found that the IDO1 inhibitor epacadostat safely reduced kynurenine-to-tryptophan ratios in advanced melanoma patients but ...

Researchers have identified a human-specific FXR-TRIM22-STAT1 checkpoint that suppresses radiation-induced antitumor immunity, and shown that the clinically approved bile acid ...

Researchers have developed fourth-generation CAR T cells targeting mucin 1 that show superior proliferation, reduced exhaustion, and enhanced tumor-killing activity ...

A review in Experimental & Molecular Medicine examines how chronic antigen exposure and a hostile tumour microenvironment reprogram T cells ...

Adelaide University researchers have developed mRNA lipid nanoparticles that reprogram immunosuppressive tumour-associated macrophages to recruit cancer-fighting T cells, showing reduced ...

A new mRNA vaccine strategy designed to activate antitumor immunity without undermining the production of vaccine antigens has shown promising ...

Physicians and scientists at the forefront of oncology research from UCLA Health Jonsson Comprehensive Cancer Center are set to unveil ...

In recent years, the complex interplay between cancer cells and the immune system has emerged as a pivotal subject in ...