Tag: cancer epigenetics

Researchers have identified that the m6A demethylase ALKBH5 stabilizes Notch2 messenger RNA under hypoxic conditions, driving ovarian cancer cell growth, ...

A dual-gene circulating cell-free DNA methylation assay targeting CACNA1E and SNTG1 detected early-stage esophageal squamous cell carcinoma with ninety percent ...

Researchers developed EpiTIL, a DNA methylation model that estimates tumor-infiltrating T lymphocytes and predicts survival outcomes in primary melanoma.

A new review describes how global transcriptional upregulation, or hypertranscription, driven by oncogene-encoded transcription factors may contribute to chromosomal instability ...

A pan-cancer analysis of 16 tumor types finds that elevated DNA methylation variability is consistently associated with genomic instability, aggressive ...

A comprehensive simulation-based evaluation of eight computational models finds that the joint location-and-scale score test JLSsc delivers the most reliable ...

Charles W.M. Roberts was elected to the National Academy of Medicine for contributions to pediatric oncology and cancer epigenetics as ...

A single-cell and epigenetic study links loss of the retinoid-binding protein CRABP1 to an invasive malignant epithelial cell state in ...

A new collection of studies shows how the dynamic epigenetic mark of DNA methylation drives and predicts diseases from rheumatoid ...

A retrospective study of 170 patients finds that synchronous chemoradiotherapy significantly extends survival in muscle-invasive urothelial carcinoma, while methylation of ...