USP7: The Double-Edged Deubiquitinase That Tumors Cannot Live Without
A new review in Cancer Cell International maps how the deubiquitinase USP7 acts as both tumor promoter and suppressor depending ...
Tag: cancer drug discovery
AI-Powered Virtual Screening Uncovers Potent New Dual CDK4/6 Cancer Inhibitor
Researchers fused machine learning, molecular docking and molecular dynamics simulations into a virtual screening pipeline that discovered HY-18,623, a nanomolar ...
Plant Compound Diosgenin Emerges as Powerful Computational Anti-Cancer Candidate
A computational screen of 698 plant compounds identified diosgenin as a stronger and safer binder of antiapoptotic Bcl-2 family proteins ...
Sage Root Compounds Trigger Self-Destruction in Breast Cancer Cells
A diterpenoid-rich fraction prepared from the roots of the Turkish sage Salvia oligophylla induced programmed cell death in MCF-7 breast ...
UCLA Researchers Win NIH Grant to Improve Cancer Immunotherapy Effectiveness
Dr. Cristina Puig-Saus and her research team at the UCLA Health Jonsson Comprehensive Cancer Center have received a five-year, $3.9 ...
AI Advances Revolutionize Oncology Drug Discovery from Targets to Therapies
The arduous journey of developing effective cancer drugs, marked by high costs and prolonged timelines, is undergoing a transformative shift ...
Exploring New Frontiers in Cancer Drug Targets Through Computational Deep Dive
In a groundbreaking study published on November 5, 2025, in npj Precision Oncology, researchers from Sanford Burnham Prebys Medical Discovery ...
Researchers Discover Promising Drug Candidates for Long-Considered ‘Undruggable’ Cancer Target
For the first time, scientists have made a groundbreaking advance in cancer research by developing drug candidates that bind irreversibly ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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