Tag: cancer cell survival pathways

A new study reports that the approved leukemia drug nilotinib binds the DNA repair protein NEIL3 to block fatty acid ...

New research shows that blocking the CXCL12/CXCR4 signaling axis in ovarian cancer cells produces a paradoxical biphasic response, with moderate ...

Researchers at Lund University have shown that pancreatic cancer cells engineered to survive detachment consistently switch on autophagy and ubiquitin ...

A comprehensive new review maps how NF-κB signalling drives breast cancer progression, subtype-specific therapy resistance and tumour-microenvironment crosstalk, and argues ...

A new review in Cancer Cell International details how the tumor suppressor RUNX3 regulates apoptosis, drug efflux, cell cycle control, ...

In a groundbreaking study poised to reshape the landscape of cancer therapeutics, researchers have unveiled a novel resistance mechanism in ...

In the ongoing battle against acute myeloid leukemia (AML), scientists are relentlessly pursuing strategies to outsmart this aggressive blood cancer. ...

In the relentless battle against glioblastoma, one of the most aggressive brain tumors known to medical science, a groundbreaking discovery ...

Mesothelioma, a particularly aggressive form of cancer primarily affecting the lining of the lungs and abdomen, continues to pose significant ...

In a groundbreaking study published recently in Nature, researchers from NYU Langone Health have unveiled a sophisticated mechanism by which ...