Tousled-Like Kinases TLK1 and TLK2 Emerge as Pan-Cancer Drivers of Genomic Instability and Immune Evasion
A pan-cancer analysis of 33 tumor types reveals that the DNA-repair kinases TLK1 and TLK2 drive genomic instability and shape ...
Tag: cancer biomarkers
Genome’s Silent Guardian: HUSH Complex Emerges as Key Player in Cancer
A systematic review in Medical Oncology details how the HUSH complex silences retrotransposons through H3K9me3 deposition and how its dysregulation ...
Mitochondrial DNA Copy Number Emerges as a Key Player in Cancer Progression
New research in The FEBS Journal links mitochondrial DNA copy number in cancer cells to mutational load, tumor growth gene ...
Massive Multi-Omics Atlas MOSAIC Maps the Hidden Diversity Inside Tumors
The MOSAIC consortium has profiled more than 2,700 tumor samples with spatial and single-cell multi-omics to build a standardized public ...
CRISPR-Cas13 Screens Reveal Hundreds of Long Non-Coding RNAs Cells Cannot Live Without
A transcriptome-scale CRISPR-Cas13 screening platform called CaRPool-seq has identified 778 essential long non-coding RNAs in human cells, including 46 required ...
New Database Reveals Hidden RNA Editing in Cancer’s Tiny Messengers
Researchers have launched EVmiRED, the first database cataloging microRNA editing events in tumor-derived extracellular vesicles, revealing that this hidden layer ...
Tumour Matrisome Emerges as a Rich Source of Cancer Biomarkers and Drug Targets
A new review in Nature Reviews Clinical Oncology details how the tumour extracellular matrix, or matrisome, drives cancer progression and ...
Neutrophil Traps That Feed Tumors: DNA Webs Emerge as Drivers and Markers of Cancer Progression
A new review details how neutrophil extracellular traps drive tumor growth, metastasis and treatment resistance while emerging as both biomarkers ...
Advanced Biosensor Detects Myeloperoxidase Using DNA Circuit
A groundbreaking advancement in biosensing technology has emerged, promising significant impacts in the field of medical diagnostics. Researchers have unveiled ...
Scientists Discover Novel Targeted Method to Halt Prostate Cancer Progression
Prostate cancer remains one of the most significant health challenges faced by men worldwide, characterized by its dependence on complex ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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