Tag: bulk RNA sequencing

Researchers identified a novel homozygous C1QB variant causing functional complement deficiency alongside a somatic TNFAIP3 variant in a pediatric lupus ...

A multi-omics study demonstrates that HLA class I expression ratios accurately differentiate hepatocellular carcinoma from normal liver tissue and correlate ...

A newly developed stabilization and micro-perfusion protocol enables high-yield single-cell and bulk transcriptomic profiling of fragile immune hemocytes from malaria-transmitting ...

In adult mouse models, concurrent chronic psychosocial stress aggravated doxorubicin-induced cardiotoxicity, resulting in combined systolic and diastolic dysfunction, elevated cardiac ...

A study in Cellular and Molecular Neurobiology identifies a C1Q/antigen-presentation-like microglial state reconfiguration in temporal lobe epilepsy with hippocampal sclerosis, ...

Stimuli that disrupt the blood-brain barrier induce human brain endothelial cells to secrete extracellular vesicles carrying both shared and stimulus-specific ...

A public-data reanalysis identified broad tumor-normal gene-expression changes in sinonasal squamous cell carcinoma and nominated four preliminary candidate biomarkers supported ...

By merging bulk and single-cell RNA sequencing with machine learning and lab experiments, researchers have identified smooth muscle cells as ...

A new computational framework quantifies why immune biomarkers that perform brilliantly in discovery datasets so often fail in clinical validation, ...

By integrating bulk and single-cell RNA sequencing with machine learning, researchers in China have identified a nine-gene macrophage signature that ...