Tag: brain aging

A new mini-review in Frontiers in Aging synthesizes evidence that brain mitochondrial decline with age is sex- and region-specific, and ...

New research shows that the age-related decline of the mitochondrial protein CHCHD2 disrupts the mitochondria-lysosome axis and drives proteostatic collapse ...

A landmark analysis of over 51,000 brain scans reveals that problematic substance use is linked to distinct, age-specific brain structural ...

A UK Biobank study of 46,843 people shows that genetic risk and lifestyle jointly drive MRI-based brain aging, with a ...

Researchers generalized Taylor's law from ecology to neural data and found that a single scaling exponent tracks how synchronized brain ...

A large longitudinal study found that chronic stress was linked to faster cognitive decline in women and Hispanic participants, while ...

A large two-cohort neuroimaging study shows that aging and Alzheimer's disease reorganize brain functional connectivity along two distinct cortical gradients, ...

NIH researchers argue that dementia may be the late-life manifestation of a systemic failure of energy regulation rather than a ...

A new review in BMC Medicine argues that disrupted lipid homeostasis is an early, measurable, and modifiable driver of brain ...

Single-nucleus RNA sequencing of the mouse brain reveals that basal forebrain cholinergic neurons undergo uniquely damaging stress-related transcriptional changes with ...