Proteomic Shifts in Macaques Reveal Alzheimer’s Targets
Proteomic analysis of aging macaques reveals region-specific molecular changes following chronic GCPII inhibition, highlighting potential therapeutic targets for sporadic Alzheimer's ...
Tag: Biomarkers
TyG Index and SII Independently Linked to Heart Disease and Mortality
A study analyzing NHANES data found the TyG index independently associated with cardiovascular disease prevalence, while the systemic immune-inflammation index ...
Four-Biomarker Score Refines Mortality Risk Prediction Across CKM Stages
A four-biomarker score integrating non-HDL cholesterol, HbA1c, eGFR, and albuminuria refines mortality risk prediction across cardiovascular-kidney-metabolic syndrome stages in a ...
AI biomarkers show promise for predicting cancer immunotherapy response, review finds
A new review finds AI-derived biomarkers show promising, though variable, performance in predicting cancer immunotherapy response across tumor types.
Urban Lifestyle Shapes Sensitive Skin Phenotypes in New Study
A cross-sectional study of 151 women in China reveals that urbanization levels and lifestyle factors significantly modulate the biological and ...
Increased CSF PKR Activation in Alzheimer’s Disease Is Associated with APOE4 Genotype
A new study using SIMOA assays finds that elevated CSF phosphorylated PKR levels in Alzheimer’s disease are associated with APOE4 ...
Plasma Metabolites May Predict Individual Treatment Responses in Psoriatic Arthritis
An exploratory analysis of baseline plasma metabolomics in eighty patients with psoriatic arthritis identified candidate biomarkers associated with individual treatment ...
Systematic Review Evaluates Explainable AI and RDoC Framework in Alzheimer’s Diagnosis
A systematic review of 56 studies demonstrates how combining explainable artificial intelligence with the Research Domain Criteria framework can map ...
Scoping review assesses metabolomics for axial spondyloarthritis
A scoping review in Advances in Rheumatology identifies specific metabolic signatures as potential tools for early diagnosis and monitoring of ...
Mitochondrial Gene Signature and NT5DC3 Predict Outcomes in Nasopharyngeal Carcinoma
A new mitochondria-related gene signature and NT5DC3 analysis identify disease prognosis and immunosuppressive traits in nasopharyngeal carcinoma.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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