AI Framework Turns Blood Protein Data Into Ageing Drug Target Hypotheses
A new six-stage computational framework called Protein Expression Net converts plasma proteomic ageing signatures from UK Biobank data into prioritized, ...
Tag: Biomarkers
Hidden messengers: matrix-bound vesicles rewrite the rules of tissue signalling
A new review argues that matrix-bound extracellular vesicles retained within the extracellular matrix form a distinct, tissue-specific signalling population with ...
Scientists Target the CD73-Adenosine Axis to Break Lung Cancer’s Immune Shield
A new review maps how the CD73-adenosine axis drives immune suppression in non-small cell lung cancer and how blocking it ...
Gut-Derived Toxin and Cytokine Patterns Track Depression Severity, Study Finds
A new study finds that gut-derived lipopolysaccharide marks mild-to-moderate depression while TNF-alpha tracks severe depression, suggesting distinct inflammatory subtypes of ...
Identification of Candidate Biomarkers and Signaling Pathways Associated with Alzheimer’s Disease Using Bioinformatics Analysis of Next Generation Sequencing Data and Molecular Docking Studies
Alzheimer's disease remains the most common cause of dementia worldwide and one of the most pressing unsolved problems in modern ...
Emotional Support Shields Teenage Girls from Early Adversity’s Metabolic Toll
A new study of 217 adolescent girls finds that strong emotional support can buffer the negative effects of early life ...
Blood Proteins May Reveal Who Benefits Most From Lung Cancer Immunotherapy
The prospective SARC-LUNG study links circulating immunometabolic biomarkers such as sRAGE and FGF21 with survival and immune microenvironment profiles in ...
Blood sugar, stress hormone and inflammation combine to dull thinking in depression
A study of 300 depression patients found that neuropeptide Y links metabolic dysfunction and inflammation to cognitive impairment in a ...
Metabolism May Predict Stress Responses Differently in Male and Female Mice
A study in adult C57Bl/6 mice finds that the metabolic profiles predicting stress responses differ between males and females, highlighting ...
Landmark Guideline Maps the Entire Journey of Anti-Cancer Drugs Through Clinical Research
A comprehensive new guideline synthesizes the full landscape of anti-cancer drug clinical research, from preclinical requirements and trial phases to ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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