Tiny RNA Cluster Revealed as Master Switch Behind Lung Cancer Survival and Immune Evasion
Researchers at the University of Bern show that the miR105/767 microRNA cluster coordinates apoptosis, cell-cycle progression, and PD-L1 expression in ...
Tag: biomarker
Genetic Study Pinpoints ASGR1 as Molecular Link Between Smoking and Heart Disease
A proteome-wide genetic study identifies the liver protein ASGR1 as a potential causal link between smoking and ischemic heart disease ...
Zinc Finger Protein ZNF154 Pushes Bladder Cancer Cells Into Ferroptosis by Suppressing a Key Survival Pathway
Researchers show that the zinc finger protein ZNF154 suppresses bladder cancer by activating PTEN transcription, blocking PI3K/AKT signaling, and triggering ...
Bile Acids Show Surprising Spike in Early Diabetic Kidney Disease, Study Finds
A cross-sectional study of 485 patients found that serum total bile acid levels rise sharply at the earliest stage of ...
Immune Checkpoint BTLA Emerges as Surprising Prognostic Marker in Ovarian Cancer
A multi-omics study identifies the immune checkpoint molecule BTLA as significantly upregulated in ovarian cancer and associated with favorable overall ...
Muscle MRI Fat Fraction Emerges as a Powerful Biomarker of Mitochondrial Myopathy Severity
A prospective study of 49 adults shows that quantitative MRI fat fraction objectively measures disease severity in mitochondrial myopathies, correlating ...
Placental Growth Factor as a Triage Test: Weighing the Clinical Evidence
A new analysis in npj Women's Health evaluates whether placental growth factor blood testing can safely and effectively triage women ...
Liver’s Master MicroRNA: How miR-122 Shapes Fatty Liver Disease, Hepatitis and Cancer
A comprehensive review shows that microRNA-122 acts as both a master regulator of liver biology and a sensitive, context-dependent biomarker ...
Invisible Epigenetic Shadow: DNA Methylation Field Effect Detected Around Kidney Tumors
Researchers report DNA methylation alterations in histologically normal kidney tissue surrounding renal cell carcinoma, supporting a field effect that may ...
ApoA2 Drives Metastasis and Drug Resistance in Liver Cancer Through HMGB1/IL-17A Signaling
New research shows that the blood lipid protein ApoA2 promotes metastasis and chemotherapy resistance in hepatocellular carcinoma by activating an ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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