Immune Markers May Flag Which Psoriasis Patients Respond Best to Ustekinumab
A retrospective study of 42 Chinese patients links the HLA-C*06:02 allele and elevated baseline IgE to faster and deeper skin ...
Tag: biologic therapy
AI model flags which severe asthma patients will not benefit from biologics
A multinational retrospective study of 801 severe asthma patients built a Random Forest model that doubled specificity in identifying likely ...
Adherence, Urban Life and Mood Tied to Remission in Rheumatoid Arthritis Cohort
A prospective cohort study in Kyrgyzstan found that medication adherence, urban residence, smoking, and depressive symptoms were independently associated with ...
Ustekinumab Shows Promise for Perianal Fistulizing Crohn’s Disease, Review Finds
A narrative review synthesizes trial and real-world evidence suggesting ustekinumab can drive fistula healing in Crohn's disease, especially when combined ...
Vunakizumab Approved in China for Moderate-to-Severe Plaque Psoriasis
Vunakizumab, a new anti-IL-17A monoclonal antibody, is approved in China for adults with moderate-to-severe chronic plaque psoriasis after phase 3 ...
Belimumab add-on therapy eased fatigue and disease activity in Saudi lupus cohort over 12 months
A prospective 12-month cohort study of 36 Saudi patients with lupus found that belimumab add-on therapy was associated with significant ...
Three Years of Lebrikizumab Kept Atopic Dermatitis Controlled in Long-Term Extension Analysis
A post hoc analysis of week 16 responders from the ADvocate trials found that most maintained deep skin and itch ...
Guselkumab clears skin in children with moderate-to-severe plaque psoriasis in phase III trial
The IL-23 blocker guselkumab significantly reduced disease severity compared with placebo in children and adolescents with moderate-to-severe plaque psoriasis in ...
Synovitis severity may steer JAK inhibitor response in difficult-to-treat rheumatoid arthritis
A small prospective biopsy study suggests high-grade synovitis may identify difficult-to-treat rheumatoid arthritis patients who respond better to JAK inhibitors ...
Many Latin American Arthritis Patients Skip Tuberculosis Screening Before Immunosuppressive Drugs
A prospective PANLAR registry study found 27% of Latin American patients with chronic inflammatory arthritis started DMARDs without tuberculosis infection ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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