Aging Clocks Need Task-Specific Tests, Not Just Age Error
A review in Biogerontology proposes evaluating molecular aging clocks as task-bound tools rather than by age-prediction error alone.
Tag: biogerontology
Fetuin-A Reduction with Pioglitazone Eases Brain Inflammation in Aged Rats with Liver-Related Cognitive Impairment
In a rat study, lowering the protein Fetuin-A with pioglitazone was accompanied by reduced hippocampal neuroinflammation and recovered recognition memory ...
Ginseng Compound Rg1 Extends Lifespan in Worms Through a DAF-16-Driven Mitophagy Pathway
A new study in Caenorhabditis elegans reports that the ginseng component ginsenoside Rg1 slows aging in the worms by activating ...
Niche Safety, Not Climate Swings, Tracks Mammalian Lifespan in Pre-Specified Comparative Test
A pre-specified phylogenetic comparison across thousands of species finds niche safety strongly associated with mammalian lifespan while environmental variability shows ...
Nine Genes Tied to Cognitive Performance Across Cortical and Subcortical Brain Tissues
A combined eQTL and GWAS analysis of cortical and subcortical brain tissues identified 117 genes linked to cognitive performance, with ...
Shared Genetic Architecture Links Fat Distribution, Ectopic Lipid Buildup and Metabolic Aging
A multivariate genomic analysis has constructed a latent genetic phenotype of adipose tissue aging from seven fat and metabolic traits, ...
New Indices Quantify How Aging and Melatonin Shape the Liver’s Regenerative Reserve
A long-term rat study introduces two composite indices that track liver regenerative potential during accelerated aging and suggest melatonin may ...
Your Eyes May Reveal a Biological Age, But What Does That Number Really Mean?
A new review in Biogerontology lays out a five-part framework for interpreting AI-derived ocular age estimates, warning that a cross-sectional ...
Why Extending Healthspan Without Lifespan Is a Misguided Goal for Aging Science
Researchers argue that the popular slogan of extending healthspan but not lifespan is scientifically incoherent and ethically untenable as a ...
New Database Maps 3,111 Genes Across the 11 Hallmarks of Aging
Researchers in India have launched AgingHallmarksDB, an interactive platform integrating 3,111 aging-associated genes across the eleven hallmarks of aging with ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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