Rituximab rescues severe PR3-ANCA pulmonary-renal syndrome when standard drugs fail
A case report details how rituximab controlled severe PR3-ANCA pulmonary-renal syndrome in a dialysis-dependent patient after conventional induction therapy failed.
Tag: B cell depletion
Rituximab’s Second Act: Rethinking B-Cell Depletion for Lupus Treatment
A new review maps where the off-label anti-CD20 antibody rituximab fits in the treatment of systemic lupus erythematosus, from refractory ...
B-Cell Depletion Therapy Reshapes Antiviral Immunity in Multiple Sclerosis, Study Finds
A cross-sectional study shows that ocrelizumab selectively contracts EBV-specific CD4 T-cell immunity in multiple sclerosis while preserving antiviral defenses against ...
After Natalizumab: Real-World Study Pits Two B-Cell Drugs Head to Head in Multiple Sclerosis
A retrospective real-world study from Milan's San Raffaele institute compares ocrelizumab and ofatumumab as successor therapies for multiple sclerosis patients ...
Two Years of Ofatumumab Reshapes the Immune Landscape in Multiple Sclerosis
A two-year real-world study found that ofatumumab sustained B-cell depletion in multiple sclerosis patients while producing significant increases in broad ...
MS Drug Ocrelizumab Linked to Rare Lung Disease in New Case Series
A new case series and literature review report that ocrelizumab, a leading multiple sclerosis therapy, is associated with a rare ...
New B Cell Therapy Shows Striking Power Against Neuromyelitis Optica
A phase III trial of obinutuzumab β shows striking efficacy in aquaporin-4-IgG-positive neuromyelitis optica spectrum disorder, deepening questions about which ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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