CAR-T Cell Therapy Pushes Beyond Blood Cancers Into Solid Tumors and Autoimmune Disease
A sweeping review charts how CAR-T cell therapy has evolved from a blood cancer breakthrough into a versatile platform tackling ...
Tag: autoimmune disease
When the Immune System Turns the Blood Against Itself
A major European review argues that autoimmune diseases such as lupus, antiphospholipid syndrome and rheumatoid arthritis drive an under-recognised burden ...
Organoids Rebuild Autoimmune Disease Tissue by Tissue, Opening a Path to Personalized Immunology
A new review maps how organoid and organ-on-a-chip platforms can reconstruct the microenvironmental logic of systemic sclerosis, lupus, and rheumatoid ...
Two Forms of the Estrogen Receptor Play Opposing Roles in Lupus Inflammation
New research shows that two splice variants of estrogen receptor alpha, ERα66 and ERα46, exert opposing, cell-type-specific and potentially sex-specific ...
mRNA Therapeutics Move Beyond Vaccines Into Cancer and Rare Disease Medicine
A new review details how mRNA therapeutics are expanding beyond infectious disease vaccines into cancer immunotherapy, protein replacement, autoimmune tolerance, ...
Early Gut Microbiome Development and Genes Together Shape Type 1 Diabetes Risk
New research in Nature Metabolism shows that the trajectory of gut microbiome maturation in early childhood interacts with a child's ...
Inebilizumab Shows Lasting Protection Against NMOSD Attacks Regardless of Prior Immunosuppressant Use
A long-term analysis of the N-MOmentum trial shows inebilizumab reduces NMOSD attack risk and disability worsening equally well in patients ...
Hidden Protein Bosses the Cleanup Crew That Keeps Lupus at Bay
Scientists have discovered that the protein FAM76B regulates macrophage clearance of dying cells through an m6A-ISG15-autophagy pathway whose failure drives ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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