New Molecular Driver of Atherosclerosis Identified: PLCE1 Pushes Artery Disease Forward
New research in Cell Death Discovery shows that the enzyme PLCE1 worsens atherosclerosis by damaging endothelial function and fueling macrophage ...
Tag: atherosclerosis
Blocking a Single Kinase May Steer Immune Cells Toward Safer Atherosclerotic Plaques
New research shows that removing protein kinase C delta reprograms macrophage metabolism to suppress inflammatory pyroptotic cell death and stabilize ...
Blood Proteins in Childhood Could Reveal Adult Heart and Metabolic Disease Risk Decades Early
A new Nature Metabolism study shows that proteomic signatures measurable in childhood predict adult cardiovascular–kidney–metabolic disease, enabling potential early prevention ...
Artery tertiary lymphoid organs encode a pathogenic high-affinity autoantibody−autoantigen pair in atherosclerosis
For decades, atherosclerosis has been understood primarily as a disease of lipids: cholesterol accumulates in the walls of large arteries, ...
Gut Microbes Emerge as Central Players in Diabetes, Heart and Brain Disease
A comprehensive review finds that gut microbial imbalance drives metabolic, neurodegenerative, cardiovascular and gastrointestinal diseases through defined metabolite signaling pathways.
Myeloid Nrf2 loss speeds atherosclerosis by boosting inflammation and hindering cell clearance
Atherosclerosis, the slow silent narrowing of the arteries that underlies most heart attacks and strokes, has long been understood as ...
Proteomics maps spatial and molecular diversity in advanced carotid artery plaques
Atherosclerosis has long been described as a disease of clogged arteries, but a new study presents a more intricate picture: ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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