How Infection Signals Push Kidney Filter Cells Into Leaks, Damage, and Cell Death
New research shows that sustained activation of the innate immune receptor TLR4 in podocytes triggers a reversible leak in the ...
Tag: apoptosis
Vaccine-Strain Measles and Mumps Viruses Team Up to Kill Colorectal Cancer Cells
A new experimental study shows that a combination of vaccine-strain measles and mumps viruses synergistically kills HT-29 colorectal cancer cells ...
Mitochondrial Complex I Emerges as a Resistance-Proof Weak Point in Parasite-Infected Cells
New research shows that inhibiting mitochondrial complex I kills Theileria annulata-infected cells, including drug-resistant ones, and reveals a conserved mitochondrial ...
Two BCL-2 Gene Variants Linked to Protein Levels and Aggressive Bladder Cancer
Brazilian researchers have found that a BCL-2 promoter variant influences protein expression in bladder tumors while a specific haplotype triples ...
Resveratrol Shields Cells From Calcium Overload and Oxidative Cell Death
A new study shows that resveratrol attenuates calcium dysregulation, oxidative stress, and apoptosis in TRPM2-expressing cells challenged with hydrogen peroxide ...
miR-486: the cardiac microRNA that shields the heart from reperfusion injury
Every year, millions of people survive heart attacks because modern medicine can reopen blocked coronary arteries with remarkable speed. Yet ...
Bacterial Peptide-Primed Stem Cell Vesicles Push Colon Cancer Cells Toward Suicide
Researchers preconditioned mesenchymal stem cells with the bacterial peptide plantaricin, producing smaller, protein-rich microvesicles that selectively triggered apoptosis in colon ...
FAS and FASL Blood Tests Fall Short as Diagnostic Biomarkers for Autoimmune Lymphoproliferative Syndrome
A new study finds that whole-blood FAS and FASL mRNA expression cannot reliably distinguish autoimmune lymphoproliferative syndrome from immune thrombocytopenia, ...
Scientists Link a DNA-Building Enzyme to Fat Rewiring and Chemotherapy Failure in Pancreatic Cancer
A new study identifies RRM2 as a gene that connects nucleotide metabolism and SREBP1/FASN-driven lipid remodeling to gemcitabine resistance in ...
Brief Limb Ischaemia Cycles Shield the Kidneys by Switching On a Mitochondrial Cleanup Pathway
New research shows that remote ischaemic preconditioning protects kidneys from reperfusion injury by activating SIRT3-dependent, Parkin-mediated mitophagy in renal tubular ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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