Tag: amyloid beta

A comprehensive review in 3 Biotech details how plant-derived compounds such as polyphenols, flavonoids, and alkaloids can inhibit the toxic ...

A new Journal of Neurology Comment argues the Alzheimer's field has avoided honestly assessing whether licensed anti-amyloid drugs deliver clinically ...

New molecular dynamics simulations show that a proline substitution and a double charge-removal mutation drive the amyloid-beta 14–23 fragment along ...

A high-sensitivity proteomic study of 66 rhesus macaques shows that blood and brain fluid age along different molecular paths, with ...

A new review maps how traditional Chinese medicine compounds simultaneously target seven core Alzheimer's disease mechanisms through a hierarchical network ...

A Mississippi State mathematician has built a validated computational model showing how copper and zinc ions influence amyloid-beta plaque formation ...

A comprehensive review in Aging Cell details how the brain's glymphatic system and meningeal lymphatic vessels govern Alzheimer's pathology and ...

A comprehensive review shows that miniaturized biosensor platforms can detect Alzheimer's, Parkinson's, and prion disease biomarkers at extraordinary sensitivity, but ...

A large APOE-stratified genome-wide association study reveals that Alzheimer's disease genetic risk variants have effects that are either amplified or ...

A new computational study in Heliyon used pharmacophore modeling of marine-derived compounds to design synthetic gamma-secretase modulators that outperformed a ...