First-in-human trial of TEAD inhibitor BPI-460372 shows early signals and safety limits
A first-in-human phase Ia trial reports that the covalent TEAD palmitoylation inhibitor BPI-460372 showed preliminary antitumor activity in advanced solid ...
Tag: advanced solid tumors
First human Phase 1 data for AI-designed ISM6331 to be presented
Insilico Medicine plans to present first human Phase 1 data for the AI-designed pan-TEAD inhibitor ISM6331 in mesothelioma and other ...
Experimental Drug Tolinapant Boosts Immunotherapy Response in Advanced Solid Tumors
A phase I trial found that the IAP antagonist tolinapant combined with pembrolizumab was well tolerated and produced a 33 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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