Intrastromal AAV genetically labels corneal sensory neurons in mouse study
A mouse study found that intrastromal adeno-associated virus delivery labeled corneal-projecting trigeminal neurons and enabled genetic tools to be expressed ...
Tag: adeno-associated virus
Spanish survey finds high DMD gene-therapy willingness amid readiness gaps
A cross-sectional survey of 53 Spanish healthcare professionals found high willingness to adopt Duchenne muscular dystrophy gene therapy, alongside concerns ...
In vivo CAR-T therapy aims to turn bespoke living drugs into universal genetic medicines
A new review charts how in vivo CAR-T engineering could transform customized living drugs into scalable, off-the-shelf genetic medicines.
Gene Therapy Shows Proof of Concept for Treating Hydrocephalus at Its Source
A University of Cincinnati and UC Davis team showed that an AAV gene therapy targeting cerebrospinal fluid-producing cells reduced hydrocephalus-related ...
Gene Therapy Restores Hearing in Congenital Deafness Trial Milestone
A new review charts the rapid rise of AAV-mediated OTOF gene replacement therapy, from the first human trials to the ...
Engineered AAV Capsid Reaches the Outer Retina Through a Simple Eye Injection
Researchers used directed evolution to create AAV5-AlyT, an adeno-associated virus variant that delivers genes efficiently to photoreceptors after minimally invasive ...
Masked AAV Vectors Switch On Gene Delivery Only Where Disease Signals Strike
Researchers have engineered adeno-associated viral vectors whose infectivity is chemically masked and restored only by liver proteases, near-infrared light or ...
Gene Therapy Tames the Brain’s Dangerous Electrical Storms
Researchers used adeno-associated virus to express the KCNN4 gene in mouse neocortex, cutting the amplitude of spreading depolarization several-fold and ...
Base Editing Corrects Gene Mutation and Slows Motor Neuron Disease in Mice
Kyoto University researchers used adenine base editing to correct the TFG mutation behind HMSN-P, delaying disease onset and extending survival ...
Gene Therapy Shows Durable Power Against Blinding Retinal Disease, Major Analysis Finds
A systematic review and meta-analysis of 25 studies finds that ocular gene therapy significantly suppresses retinal neovascularization and vascular leakage ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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