Engineered AAV Capsid Reaches the Outer Retina Through a Simple Eye Injection
Researchers used directed evolution to create AAV5-AlyT, an adeno-associated virus variant that delivers genes efficiently to photoreceptors after minimally invasive ...
Tag: adeno-associated virus
Masked AAV Vectors Switch On Gene Delivery Only Where Disease Signals Strike
Researchers have engineered adeno-associated viral vectors whose infectivity is chemically masked and restored only by liver proteases, near-infrared light or ...
Gene Therapy Tames the Brain’s Dangerous Electrical Storms
Researchers used adeno-associated virus to express the KCNN4 gene in mouse neocortex, cutting the amplitude of spreading depolarization several-fold and ...
Base Editing Corrects Gene Mutation and Slows Motor Neuron Disease in Mice
Kyoto University researchers used adenine base editing to correct the TFG mutation behind HMSN-P, delaying disease onset and extending survival ...
Gene Therapy Shows Durable Power Against Blinding Retinal Disease, Major Analysis Finds
A systematic review and meta-analysis of 25 studies finds that ocular gene therapy significantly suppresses retinal neovascularization and vascular leakage ...
Light-Sensitive Genes Offer New Hope for Restoring Vision in Blind Patients
A new Gene Therapy review charts how mutation-agnostic optogenetic gene therapy could restore vision in blind patients, while detailing the ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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