Systematic Review Uncovers How ATM Gene Defects Shape Blood Cancers
A new systematic review finds that mutations, methylation, and expression loss of the ATM DNA repair gene are recurrent and ...
Tag: acute myeloid leukemia
Stem Cell Transplant Cured a Girl’s Leukemia but Left Her Friedreich Ataxia Unchanged
A decade-long case report shows that allogeneic stem cell transplantation cured a Friedreich's ataxia patient's leukemia and normalized her blood ...
Single-Cell Map Reveals Five Macrophage States Behind Chemotherapy Resistance in AML
Single-cell RNA sequencing of post-chemotherapy AML bone marrow has identified five macrophage polarization states whose abundance tracks with treatment response ...
Two Decades of Data Show Steady Gains in Survival After Stem Cell Transplants for Leukemia
A national cohort study of 1,112 Austrian AML patients spanning 2000 to 2017 shows gradual improvements in five-year survival after ...
Severe Leukemia Drug CPX-351 Linked to Rare Hypersensitivity Reaction in New Case Report
A new case report describes a possible CPX-351-associated DRESS/DIHS-like reaction in a leukemia patient who developed the syndrome despite severe ...
Children With Down Syndrome Face 150-Fold Higher Leukemia Risk, and a Landmark Turkish Study Shows Why Getting the Diagnosis Right Saves Lives
A nationwide Turkish cohort study of 53 children with Down syndrome shows that those with Down syndrome-related myeloid leukemia achieved ...
ICU Care for Acute Leukemia Is No Longer a Death Sentence, Landmark Analysis Shows
A massive individual participant data meta-analysis of over 2,000 critically ill patients with acute leukemia shows ICU mortality falling over ...
Histamine Receptor Signaling Could Resensitize Resistant Leukemia Cells to Glucocorticoids
New research shows that histamine H2 receptor signaling can amplify glucocorticoid receptor activity and resensitize cytarabine-resistant leukemia cells to low-dose ...
Apoptosis Gene Patterns Reveal Distinct AML Subgroups and Flag BIK as a Surprising Prognostic Marker
A new study of 90 AML patients shows that apoptosis gene expression patterns define two biologically distinct leukemia subgroups with ...
Epigenetic Variation Shapes Chromatin in Acute Myeloid Leukemia
A groundbreaking multiomics study has unraveled the intricate epigenetic and transcriptional landscapes of acute myeloid leukemia (AML) at single-cell resolution, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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