How leukemia hijacks the bone marrow niche to hide from therapy
A new review details how acute myeloid leukemia remodels the bone marrow microenvironment to shelter both bulk blasts and leukemic ...
Tag: acute myeloid leukemia
Early Stem Cell Transplants Boost Survival in Shwachman-Diamond Syndrome
A large international study finds that performing stem cell transplants soon after high-risk bone marrow features emerge dramatically improves survival ...
Scientists Map Two Distinct T Cell Exhaustion Programs Driving AML Relapse Before and After Transplant
Single-cell sequencing reveals that self-derived and donor-derived exhausted T cells in acute myeloid leukemia run on different transcriptional programs, with ...
Hospital at Home Lets Leukemia Patients Recover Safely Outside the Ward
A Swedish study found that intensively treated acute myeloid leukemia patients managed at home through a hospital-at-home program spent half ...
Microbial RNA in Blood Reveals Hidden Clues About Leukemia Treatment Response
A new study of microbial RNA in the blood of leukemia patients suggests that the circulating metatranscriptome may carry information ...
Donor Lymphocyte Infusions Match Second Transplants After Leukemia Relapse, Study Finds
A matched single-center comparison of 85 relapsed patients finds no significant overall survival difference between therapeutic donor lymphocyte infusion and ...
New AI Framework Maps Drug Sensitivity Down to Individual Cells in Bulk Tumor Samples
A new two-step machine-learning framework called CLIMB and CLIFF computationally deconvolves bulk RNA-seq and drug sensitivity data into cell-type and ...
Thirteen Years of Infection Data Reveal a Safer Path for Leukemia Induction Therapy
A 13-year Polish study of 219 acute myeloid leukemia patients shows that stopping fluoroquinolone prophylaxis in 2018 was clinically safe, ...
How the Bone Marrow Niche Shields Acute Myeloid Leukemia From Chemotherapy
A comprehensive review reveals how leukemic cells hijack the bone marrow microenvironment to survive chemotherapy, highlighting the CXCL12–CXCR4 axis, stromal ...
Venetoclax Combo Extends Life in Bulgarian AML Patients but at a Steep Price, Real-World Model Finds
A Bulgarian real-world economic model finds that venetoclax plus azacitidine improves survival and quality of life in older AML patients ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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