Iron, Lipids and Cell Death: Ferroptosis Biomarkers Emerge as Clues to Vitiligo Activity
A new case-control study finds that serum markers of ferroptosis, including ACSL4, MDA and ROS, are elevated in vitiligo vulgaris ...
Tag: ACSL4
Lactate Fuels a Deadly Feedback Loop That Drives Gut Damage in Ulcerative Colitis
A new study in Genome Medicine reveals that lactate produced by inflamed gut cells fuels an ACSS2-driven histone lactylation feedback ...
Four Metabolic Genes Predict Survival in Aggressive Liver Cancer
Researchers have built and validated a four-gene metabolic signature that predicts survival in intrahepatic cholangiocarcinoma more accurately than standard clinical ...
Desert Plant Compound Shows Promise Against Depression by Protecting the Gut
Total glycosides from Cistanche tubulosa relieved depressive-like behaviors and gut dysfunction in stressed mice by suppressing intestinal ACSL4-mediated ferroptosis through ...
Hidden Protein Modification Lets Pancreatic Cancer Evade Ferroptosis and Resist Chemotherapy
A new Nature Cancer study reveals how hypoxia-induced lactylation of MMSDH triggers ACSL4 degradation through propionylation, helping pancreatic cancer evade ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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