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Home Science News Cancer

Study Finds Cancer Screenings Persist Long After Guidelines Shift to Reduce Unnecessary Tests

June 9, 2025
in Cancer
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Cancer screening has long been heralded as a cornerstone of preventative medicine, promising early detection and improved patient outcomes. However, a groundbreaking new study published in BMJ Quality & Safety highlights a startling reality: rolling back low-value or unnecessary cancer screening practices can take over a decade, sometimes as long as 13 years or more, even after the release of updated clinical guidelines that recommend against them. This slow pace of change presents significant challenges for both healthcare providers and patients alike, underscoring a critical issue in efforts to optimize cancer diagnostics and patient care.

Unnecessary cancer screenings are not mere redundancies; they pose tangible risks to patients. Overdiagnosis, which refers to the identification of cancers that would not have caused harm during a patient’s lifetime, leads to psychological distress, unwarranted invasive procedures, and toxic treatments that carry their own health risks. These screenings also contribute to escalating healthcare costs and anxiety among patients, fueling a cycle of fear and overtreatment rather than evidence-based care. The new study, led by Dr. Jennifer LeLaurin from the University of Florida’s health outcomes and biomedical informatics division, explores deeply the sluggish process of discontinuing these practices despite clear guideline recommendations.

Dr. LeLaurin and her team, supported by the National Cancer Institute’s Consortium for Cancer Implementation Science, conducted an extensive data analysis of screening behaviors surrounding cervical and prostate cancers. The research meticulously examines the impact of guideline changes that recommended avoiding cervical cancer screening in women under 21 and over 65 years, as well as discouraging prostate cancer screening in men aged 70 and older. These guidelines stem from rigorous evaluations by the United States Preventive Services Task Force (USPSTF), an independent body that grades screening tests based on their net benefit or harm.

The findings reveal a striking disparity in the speed at which clinical practice adapts to new recommendations. While cervical cancer screening rates among younger women plummeted by 50% within a year following the guideline update, screening among women older than 65 experienced a lag that extended over 13 years to achieve a similar reduction. More concerning, prostate cancer screenings in men over 70 have stubbornly persisted without a 50% decline even more than a decade after the 2012 recommendations advised against routine testing in this group. This inertia reflects complex barriers rooted in both provider and patient behavior.

Several factors contribute to this entrenched continuation of outdated screening practices. Physicians often face difficulty abandoning long-standing routines, especially when reinforced by patient expectations shaped by years of public health messaging emphasizing early detection. Furthermore, the regular shifts in screening guidelines generate confusion for clinicians and patients alike, complicating conversations about risk-benefit profiles. The psychological weight of potentially missing a cancer diagnosis fuels conservative tendencies toward maintaining screenings, despite emerging evidence that some are low value or detrimental.

One segment of the research particularly underscores the technological and systemic gaps in monitoring the use of other cancer screenings, such as those for ovarian, thyroid, testicular, and pancreatic cancers. These cancers lack robust tracking mechanisms that reliably capture data on whether screening continues post-guideline changes. Consequently, the true scope of unnecessary or inappropriate testing for these cancers remains elusive. Dr. LeLaurin emphasizes the pressing need for enhanced data infrastructure to illuminate where and how low-value screenings persist, enabling targeted interventions.

The USPSTF plays a pivotal role in shaping cancer screening paradigms in the United States. This independent task force systematically reviews emerging evidence and rates screening procedures on a grading scale where a “D” signifies strong recommendations against routine use in specific populations due to lack of benefit or potential harm. Between 1996 and 2012, this task force released numerous guidelines restricting screening in asymptomatic individuals for cancers such as ovarian, thyroid, testicular, and pancreatic, in addition to refining age parameters for cervical and prostate cancer screenings. Yet, implementing these guidelines in everyday clinical practice remains a significant challenge.

Beyond clinical inertia and patient expectations, the study highlights the potential value in reexamining incentive structures within healthcare that may inadvertently encourage excessive screening. Current reimbursement models, quality metrics, and defensive medicine practices can contribute to overtesting. According to Dr. LeLaurin, meaningful progress requires not only improving education for both providers and patients but also considering policy-level changes that disincentivize the continuation of low-value and potentially harmful cancer screenings.

These findings hold broad implications for the future of cancer care and public health strategies. They emphasize that simply issuing guidelines is insufficient to alter entrenched clinical practices swiftly. Successful de-implementation of outdated screenings demands multifaceted approaches, including systems for real-time monitoring of screening practices, streamlined educational initiatives, and thoughtful communication strategies that engage patients in understanding the nuanced benefits and risks of cancer screening.

The research also adds to the ongoing debate about precision medicine and risk stratification, highlighting the need to tailor screening recommendations to individual risk profiles rather than relying on broad age-based cutoffs alone. Integrating advanced informatics tools and leveraging big data may offer solutions for dynamically adjusting screening practices and accelerating the adoption of evidence-based recommendations. However, overcoming deeply rooted cultural perceptions about cancer detection remains a formidable hurdle.

Ultimately, this narrative review shines a spotlight on the complexity of altering healthcare behaviors in the realm of cancer screening. The extended timeline required to fully de-implement non-beneficial screenings demonstrates that evidence-based medicine must contend with human factors, institutional inertia, and systemic challenges. With breast cancer screening debates and other cancer prevention efforts continuing to evolve, the message from Dr. LeLaurin and her colleagues is clear: reducing harm and promoting patient-centered care in oncology demands patience, innovation, and unwavering commitment to translating science into practice.


Subject of Research: People
Article Title: Time to de-implementation of low-value cancer screening practices: a narrative review
News Publication Date: 20-May-2025
Web References: 10.1136/bmjqs-2025-018558
References: BMJ Quality & Safety, 2025, DOI: 10.1136/bmjqs-2025-018558
Keywords: Cancer screening, Oncology, Cancer risk, Cancer patients, Prostate cancer, Cervical cancer, Ovarian cancer, Thyroid cancer, Pancreatic cancer, Testicles

Tags: BMJ Quality & Safety studycancer diagnostic practicescancer screening guidelinesDr. Jennifer LeLaurin researchevidence-based cancer carehealthcare cost escalationhealthcare provider challengeslong-term effects of cancer screeningoverdiagnosis in cancerpatient care optimizationpsychological distress from screeningsunnecessary cancer screenings
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