About The Study: In this cross-sectional cohort study of 170 former football players and 54 unexposed controls, larger perivascular space (PVS) volume was associated with greater exposure to repetitive head impacts (RHI). Additionally, PVS volume was associated with worse performance on cognitive tests. These findings suggest that PVS volume may contribute to the association between exposure to RHI, cognitive impairment, and the development of RHI-associated neurodegeneration.
About The Study: In this cross-sectional cohort study of 170 former football players and 54 unexposed controls, larger perivascular space (PVS) volume was associated with greater exposure to repetitive head impacts (RHI). Additionally, PVS volume was associated with worse performance on cognitive tests. These findings suggest that PVS volume may contribute to the association between exposure to RHI, cognitive impairment, and the development of RHI-associated neurodegeneration.
Corresponding Author: To contact the corresponding author, Inga K. Koerte, MD, PhD, email ikoerte@bwh.harvard.edu.
To access the embargoed study: Visit our For The Media website at this link
(doi:10.1001/jamanetworkopen.2024.28687)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
Journal
JAMA Network Open
Discover more from Science
Subscribe to get the latest posts sent to your email.