In the realm of geriatric medicine, the term “muscle quality” has emerged as a focal point for ongoing research and clinical discussion. Traditionally applied to assess muscle health in older adults, the term has elicited diverse interpretations and implications. A recent paper by Costa-Pereira et al. attempts to refine this concept, suggesting that muscle quality should not be merely evaluated in terms of quantity but should also encompass functional performance and the biological characteristics of muscle tissue. This paradigm shift has the potential to significantly affect how healthcare providers approach aging populations, particularly regarding mobility, independence, and overall quality of life.
Historically, muscle mass has been the primary metric used to assess muscular health, primarily due to the straightforward measurement techniques available. However, an increasing body of research indicates that this single-dimensional view is insufficient. It neglects essential factors such as muscle fiber composition, the presence of intramuscular fat, and the muscle’s metabolic capacity. Costa-Pereira and colleagues argue that muscle quality must be defined through a more comprehensive lens, which includes functional assessments that correlate more closely with mobility and physical capabilities in geriatric patients.
To delve deeper into the nuances of muscle quality, the authors highlight recent advancements in the understanding of muscle tissue at the micro-level. Utilizing imaging techniques and histological analyses, researchers have been able to demonstrate that muscle fibers can vary significantly in their metabolic demands and functional outcomes. For instance, the presence of type I and type II muscle fibers showcases distinct capabilities, with type I fibers being advantageous for endurance and type II fibers for strength and power. This underlying complexity necessitates a re-evaluation of how muscle health assessments are conducted in older adults.
Another aspect discussed in the article is the role of inflammation and its impact on muscle quality. Chronic inflammation, often present in aging individuals, can alter muscle metabolism and contribute to the deterioration of muscle function. By incorporating measures of systemic inflammation into the assessment of muscle quality, healthcare professionals can achieve a more holistic understanding of a patient’s health status. This approach prioritizes not just the quantity of muscle but its functional capability in light of systemic health conditions.
Moreover, the interplay between nutrition and muscle quality is a critical point addressed by Costa-Pereira et al. Adequate protein intake, alongside key micronutrients such as vitamin D, has been associated with improved muscle function. The researchers advocate for dietary assessments to become integral to muscle quality evaluations. By recognizing the importance of nutrition, medical professionals can develop comprehensive care plans that include dietary recommendations alongside physical rehabilitation strategies.
Physical activity, particularly strength training and resistance exercises, is another pillar of maintaining muscle quality in older adults. Studies have shown that targeted exercise regimens can restore muscle function and improve quality of life significantly. This presents a compelling argument for the widespread implementation of customized exercise programs tailored to individual capabilities and health conditions. The authors emphasize the need for geriatric practitioners to incorporate exercise prescriptions into routine assessments for older adults, thereby addressing muscle quality in a proactive manner.
The article also acknowledges the psychological dimensions of muscle quality and physical activity. Mental well-being, motivation, and self-perception of physical health can significantly influence an older adult’s willingness to engage in physical activity. Therefore, fostering a supportive environment that encourages exercise participation is essential for improving the overall muscle quality and health of this population. This emphasizes a holistic approach to healthcare that intertwines physical and mental health paradigms.
In terms of clinical applications, the insights provided by Costa-Pereira et al. lay the groundwork for developing standardized protocols for assessing muscle quality. Health professionals can leverage these guidelines to create evidence-based practices tailored to the unique needs of older patients. The authors envision a future where assessments of muscle quality are integrated into periodic health evaluations, enabling early detection of functional decline and the implementation of timely interventions.
As the dialogue on muscle quality continues to evolve, it is evident that further research is essential for validating these concepts and refining methodologies. Future studies should aim to establish strong correlations between muscle quality indicators and clinical outcomes such as falls, hospitalizations, and overall longevity. This will deepen the understanding of how muscle quality directly contributes to the health of the aging population.
Feedback from a variety of stakeholders, including geriatricians, physiotherapists, and nutritionists, is vital in disseminating the emerging concept of muscle quality. Engaging in interdisciplinary discussions can lead to the identification of best practices and innovative care strategies that transcend traditional boundaries. Collaborative efforts within healthcare communities can serve to advance the discourse on muscle quality while fostering a shared commitment to enhancing the lives of older adults.
In conclusion, Costa-Pereira et al. present a compelling case for rethinking muscle quality, advocating for a comprehensive understanding that encompasses multiple determinants of muscular health. By integrating assessments of functional performance, nutrition, and psychological well-being, healthcare professionals can shift their focus toward more holistic care for older adults. The implications of this work resonate far beyond single assessments; they carry the potential to redefine standards of care and improve the quality of life for aging populations worldwide.
As the scientific community continues to grapple with the intricacies of muscle health, one thing is clear: the reevaluation of muscle quality is not just timely but essential in the quest for better geriatric care. Through ongoing research and dialogue, the aspiration to foster healthier, more active aging populations can evolve from a theoretical ideal into a tangible reality.
Subject of Research: Muscle quality in older adults
Article Title: “Muscle quality”: rethinking an imprecise term.
Article References: Costa-Pereira, J.P., Cristina Gonzalez, M., Cruz-Jentoft, A.J. et al. “Muscle quality”: rethinking an imprecise term. Eur Geriatr Med (2025). https://doi.org/10.1007/s41999-025-01373-y
Image Credits: AI Generated
DOI: 10.1007/s41999-025-01373-y
Keywords: muscle quality, geriatric medicine, muscle health, physical performance, nutrition, inflammation, exercise, interdisciplinary approach.

