About The Study: This study including 903 women with BRCA germline pathogenic variants found that a breast cancer diagnosis less than 10 years postpartum was associated with higher risk of mortality compared with nulliparous women and women diagnosed at least 10 years postpartum. These results should inform genetic counseling, prevention, and treatment strategies for BRCA pathogenic variant carriers.
About The Study: This study including 903 women with BRCA germline pathogenic variants found that a breast cancer diagnosis less than 10 years postpartum was associated with higher risk of mortality compared with nulliparous women and women diagnosed at least 10 years postpartum. These results should inform genetic counseling, prevention, and treatment strategies for BRCA pathogenic variant carriers.
Authors: Zhenzhen Zhang, Ph.D., of Oregon Health & Science University in Portland, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2024.7421)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
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