About The Study: The results of this cohort study suggest that combining plasma p-tau217 and Aβ42/40 levels could be useful for predicting development of Aβ pathology in people with early stages of subthreshold Aβ accumulation. These biomarkers might thus facilitate screening of participants for future primary prevention trials.
About The Study: The results of this cohort study suggest that combining plasma p-tau217 and Aβ42/40 levels could be useful for predicting development of Aβ pathology in people with early stages of subthreshold Aβ accumulation. These biomarkers might thus facilitate screening of participants for future primary prevention trials.
Corresponding Authors: To contact the corresponding authors, email Oskar Hansson, M.D, Ph.D. (Oskar.Hansson@med.lu.se) and Shorena Janelidze, Ph.D. (shorena.janelidze@med.lu.se).
To access the embargoed study: Visit our For The Media website at this link
(doi:10.1001/jamaneurol.2024.2619)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Media advisory: This study is being presented at the Alzheimer’s Association International Conference.
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Journal
JAMA Neurology
Cite Scienmag News
Cassandra Pierce. (July 28, 2024). Plasma phosphorylated tau 217 and Aβ42/40 to predict early brain Aβ accumulation in people without cognitive impairment. Scienmag. https://scienmag.com/plasma-phosphorylated-tau-217-and-a%ce%b242-40-to-predict-early-brain-a%ce%b2-accumulation-in-people-without-cognitive-impairment/
Cassandra Pierce. "Plasma phosphorylated tau 217 and Aβ42/40 to predict early brain Aβ accumulation in people without cognitive impairment." Scienmag, 28 July 2024, https://scienmag.com/plasma-phosphorylated-tau-217-and-a%ce%b242-40-to-predict-early-brain-a%ce%b2-accumulation-in-people-without-cognitive-impairment/. Accessed 3 September 2026.
Cassandra Pierce. "Plasma phosphorylated tau 217 and Aβ42/40 to predict early brain Aβ accumulation in people without cognitive impairment." Scienmag. July 28, 2024. https://scienmag.com/plasma-phosphorylated-tau-217-and-a%ce%b242-40-to-predict-early-brain-a%ce%b2-accumulation-in-people-without-cognitive-impairment/
