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Incidence of dementia before age 65 years among World Trade Center attack responders

June 12, 2024
in Medicine
Cassandra Pierce
By Cassandra Pierce Scienmag Editorial Profile - Systems Neuroscience
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About The Study: In this cohort study of World Trade Center responders who survived these unique exposures and participated in a longitudinal follow-up study of cognition from 2014 through 2022, when compared with responders with the lowest exposure levels or responders who used personalized protective equipment (PPE), more severe exposure to dust or debris was significantly associated with a higher risk of dementia before 65 years of age. This study suggests that the reliable use of PPE might help prevent the onset of dementia before age 65 years among individuals exposed to an uncontrolled building collapse. Future research is warranted to determine cerebral biomarkers for individuals with exposure-associated dementia.

About The Study: In this cohort study of World Trade Center responders who survived these unique exposures and participated in a longitudinal follow-up study of cognition from 2014 through 2022, when compared with responders with the lowest exposure levels or responders who used personalized protective equipment (PPE), more severe exposure to dust or debris was significantly associated with a higher risk of dementia before 65 years of age. This study suggests that the reliable use of PPE might help prevent the onset of dementia before age 65 years among individuals exposed to an uncontrolled building collapse. Future research is warranted to determine cerebral biomarkers for individuals with exposure-associated dementia.

Corresponding Author: To contact the corresponding author, Sean A. P. Clouston, Ph.D., email sean.clouston@stonybrookmedicine.edu.

To access the embargoed study: Visit our For The Media website at this link

(doi:10.1001/jamanetworkopen.2024.16504)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time 

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 



Journal

JAMA Network Open

Subject of Research: Medicine

Article Title: Incidence of dementia before age 65 years among World Trade Center attack responders

Article References: Original research article

Image Credits: AI Generated

DOI: Not provided

Keywords: Not provided

Cite Scienmag News

Cassandra Pierce. (June 12, 2024). Incidence of dementia before age 65 years among World Trade Center attack responders. Scienmag. https://scienmag.com/incidence-of-dementia-before-age-65-years-among-world-trade-center-attack-responders/

Cassandra Pierce. "Incidence of dementia before age 65 years among World Trade Center attack responders." Scienmag, 12 June 2024, https://scienmag.com/incidence-of-dementia-before-age-65-years-among-world-trade-center-attack-responders/. Accessed 5 September 2026.

Cassandra Pierce. "Incidence of dementia before age 65 years among World Trade Center attack responders." Scienmag. June 12, 2024. https://scienmag.com/incidence-of-dementia-before-age-65-years-among-world-trade-center-attack-responders/

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