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cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy

July 29, 2026
in Medicine
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cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy

cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy

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Huang, Y., Fan, L., Wong, M.Y. et al. cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy.
Nat Neurosci (2026). https://doi.org/10.1038/s41593-026-02384-z

https://doi.org/10.1038/s41593-026-02384-z

Tags: cGAS-mediated immune response in epilepsydisease progression in refractory epilepsyimmune-mediated neurodegenerationinnate immune pathways in neurological disordersinnate immunity and seizure disordersmolecular mechanisms of drug-refractory epilepsyneuroimmune interactions in epilepsyneuroinflammation and epilepsy progressionneuroinflammatory signaling pathwaysrole of cGAS-STING pathway in epilepsytherapeutic targets for drug-resistant epilepsytype I interferon signaling in drug-resistant epilepsy
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