Medicine
Genetic Framework Flags Safety Risks for Inflammatory Bowel Disease Drug Targets
A new genetics-based framework systematically flags potential safety risks for inflammatory bowel disease drug targets before broad clinical exposure.
Lactate Fuels a Deadly Feedback Loop That Drives Gut Damage in Ulcerative Colitis
A new study in Genome Medicine reveals that lactate produced by inflamed gut cells fuels an ACSS2-driven histone lactylation feedback...
Enlarged Choroid Plexus Reveals Hidden Brain Inflammation in Small Vessel Disease
New MRI research shows that the choroid plexus is enlarged and actively inflamed in cerebral small vessel disease, linking the...
Common Sugar Molecule Uridine Shows Promise Against Deadly Lung Scarring
A new multiomics and machine learning study suggests the natural nucleoside uridine may ease pulmonary fibrosis by directly engaging MMP7...
Why Iran’s Parliament Struggles to Shape Health Policy: A Power Analysis
A qualitative study of 32 Iranian health policy actors using Gaventa's power cube framework reveals how closed decision spaces, fragmented...
Diabetes Drugs That Quietly Lower Blood Pressure: Inside the GLP-1 Mechanism
A new review synthesizes molecular, renal and clinical evidence showing that GLP-1 receptor agonists lower systolic blood pressure through converging...
Better Diet Quality Linked to Lower Heart Risk in Overweight Adults, Study Finds
A cross-sectional study of 672 overweight and obese Iranian adults found that higher diet quality, measured by the Lifelines Diet...
Vitamin C Infusion Restores Aging Brain Blood Vessel Function in Small Trial
A randomized crossover trial found that high-dose intravenous vitamin C improved cerebrovascular reactivity in middle-aged and older adults but not...
First Standardized Antibiogram from Somaliland Reveals Alarming Antibiotic Resistance
The first CLSI M39-A4-compliant cumulative antibiogram from Somaliland reveals high resistance to ampicillin and ciprofloxacin and reduced meropenem susceptibility among...
Oocyte Gene Figla May Steer Ovarian Reserve Formation Through Ywhab, Mouse Study Suggests
A new mouse and cell study identifies Ywhab as a candidate downstream target of the oocyte transcription factor Figla during...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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