Medicine
Why Some African Hospitals Save Far More Newborn Lives Than Others
A qualitative study of 16 hospitals in Kenya, Malawi, Nigeria and Tanzania identifies 114 mostly low-cost strategies, from peer mentorship...
Fertility-Sparing Surgery Holds Its Ground Against a Rare Ovarian Tumor
A retrospective cohort of 186 patients with seromucinous borderline ovarian tumors found that cystectomy and unilateral salpingo-oophorectomy showed no significant...
Simulated Patients Replace Human Trials in Virtual Test of Roxithromycin Drug Equivalence
Chinese researchers validated a physiologically based pharmacokinetic model of roxithromycin and used it to run a virtual bioequivalence trial in...
Deadly Fungal Eye Infection Strikes Healthy Greenhouse Worker, Doctors Warn
A 30-year-old Iranian greenhouse worker with no immune deficits lost his eye socket to invasive Rhizopus infection, highlighting occupational mold...
Blood Tests That Read the Brain: A Roadmap for Molecular Biomarkers in Stroke Care
A new Nature Reviews Neurology roadmap charts how blood-based molecular biomarkers of brain injury, metabolism, inflammation and gut dysbiosis could...
Prostate Cancer Drug Enzalutamide Extends Lives but Fails the Cost-Effectiveness Test at Current Prices
A within-trial economic analysis of the ENZAMET phase 3 trial finds that enzalutamide significantly extends survival in metastatic hormone-sensitive prostate...
Antidepressants and Breast Cancer: Landmark Analysis of Nearly Two Million Women Reveals Timing Matters
A meta-analysis of twenty-three studies covering nearly 1.83 million women finds that short-term SSRI use is associated with a modest...
Mouse Models Show Teeth Can Expose Hidden Signs of Rare Bone Disease
New knock-in mouse models of hypophosphatasia show that specific ALPL gene variants shape dental symptoms independently of blood enzyme levels,...
The Dark Side of Good Cholesterol: Rogue HDL Particle Drives Arterial Aging
Scientists have identified an electronegative HDL subfraction enriched in apolipoprotein(a) that induces endothelial senescence through the p53–p21 pathway and accelerates...
How Gravity Sculpts Crops: New Insights Could Reshape Maize Breeding
A comprehensive review maps the molecular machinery of plant gravitropism and predicts 69 candidate genes that could let breeders engineer...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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