Cancer
Macrophage-to-myofibroblast transition-derived itaconate drives lung cancer bone metastasis via HSPA8
Lung cancer’s spread to bone is one of the most destructive stages of the disease, often causing severe pain, fractures,...
Cold Spring Harbor, Northwell Health lead development of 150+ cancer treatment models
A decade-long international effort has produced the largest publicly available collection of patient-derived cancer organoids to date, giving researchers a...
Study reveals HHV-8-driven immune regulation in HIV-associated and classic Kaposi sarcoma
Kaposi sarcoma is not simply a tumour made of abnormal blood vessels. It is a complex tissue ecosystem in which...
TMEM135 Deficiency Prevents Intestinal Fat Buildup Through ELOVL6-Driven PPARα Lipid Oxidation
A molecular switch that helps the intestine manage incoming fat may have been identified in an unexpected place: the activity...
Experimental drug weaponizes cancer’s sugar addiction against tumors
Cancer cells are often described as metabolic opportunists, consuming extraordinary amounts of glucose to sustain rapid growth. A new experimental...
Cancer Cells Use Fatty Acid to Evade Immune Attacks in Liver Metastases
Liver metastases are among the most difficult complications of cancer to treat, but researchers in Belgium and their international collaborators...
Early Trial Tests Ontorpacept Plus Doxorubicin for Advanced Leiomyosarcoma
A new Phase 1/2 clinical study is testing whether an immune-targeting drug can make chemotherapy more effective against high-grade leiomyosarcoma,...
CD44’s Diverse Roles in Cancer Progression and Targeted Treatment Strategies
Cancer researchers are turning renewed attention to one of the most versatile molecules on the surface of malignant cells: CD44....
Sylvester Cancer Center Ranks First in Florida, 23rd Nationally for Cancer Care
Sylvester Comprehensive Cancer Center, part of UHealth – University of Miami Health System, has been named the No. 1 cancer...
Study suggests Viagra may reduce cancer spread
Viagra, one of the world’s most recognizable medicines, may have an unexpected role beyond treating erectile dysfunction. Scientists at the...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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