Cancer
AI Reveals Why Pathologists Disagree on HER2 Scoring in Breast Cancer
A Brazilian study found that an AI model's measure of HER2 staining heterogeneity within breast cancer samples predicts where pathologists...
Pan-Cancer Cell Atlas Shows How Tumors Team Up to Colonize Bone
A pan-cancer single-cell atlas of nearly 900,000 cells shows that bone metastases from ten cancer types share convergent malignant programs...
Circular RNA Revealed as Hidden Brake on Colorectal Cancer Growth
Researchers report that the circular RNA circMTCL1, sharply depleted in colorectal cancer tumors, suppresses cancer cell growth by sponging miR-145-5p,...
PET tracer lights up ferroptosis to track liver cancer immunotherapy in real time
Researchers combined anti-PD-L1 immunotherapy with the PARP inhibitor Olaparib to trigger ferroptosis in liver cancer and used the SLC7A11-targeted PET...
Experts map the real-world path to treating fear of cancer’s return
A three-round Delphi study of Australian health professionals has identified the feasibility, barriers, and implementation strategies needed to deliver a...
The Brain’s Motor Highway Moves as Glioma Returns, Study Finds
A longitudinal diffusion tensor imaging study of 29 high-grade glioma patients shows that the healthy-side corticospinal tract shifts anteriorly by...
Pancreatic Cancer Reshapes Nerves Beyond the Tumor, Study Finds
A prospective study of 92 pancreatoduodenectomy specimens shows that pancreatic ductal adenocarcinoma is associated with significantly increased density of nerves...
How aging and sex reshape the immune system’s fight against cancer
A new Nature Aging study from Mass General Brigham shows that male and female immune systems age differently, with earlier...
Why EGFR Drugs Fail in Glioblastoma: A STAT3 Escape Route Takes Center Stage
A new review argues that glioblastoma evades EGFR-targeted therapies through compensatory STAT3 activation, positioning the EGFR–STAT3 axis as an adaptive...
The Golgi Apparatus Emerges as a Hidden Driver of Alzheimer’s Disease
A new review argues that the long-overlooked Golgi apparatus, supported by human genetic, proteomic, and lipidomic evidence, may be a...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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