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Browsing Category
Cancer
Massey researchers review geographic factors that affect HPV vaccination rates
Human papillomavirus (HPV) is the most common sexually transmitted infection, with an estimated 79 million Americans currently infected with the virus, according to the Centers for Disease Control and Prevention. If a high-risk HPV…
New maintenance treatment for acute myeloid leukemia prolongs the lives of patients
Credit: WCM Patients with acute myeloid leukemia (AML), the most common form of acute leukemia in adults, that has gone into remission following initial chemotherapy remain in remission longer and have improved overall survival when…
CT identifies patients with high-risk nonalcoholic fatty liver disease (NAFLD)
Multiparametric CT findings can distinguish patients with high-risk NAFLD (advanced fibrosis or cirrhosis); however, the presence of nonalcoholic steatohepatitis (NASH) remains elusive for the modalityCredit: American Roentgen Ray Society…
The Lancet and The Lancet Oncology: Global demand for cancer surgery set to grow by almost 5 million…
A modelling study suggests that demand for cancer surgery will rise by 52% - equal to 4.7 million procedures - between 2018 and 2040, with the greatest relative increase in low-income countries, which already have substantially lower…
New combination of immunotherapies shows great promise for treating lung cancer
Researchers at Canada's McMaster University use one immunotherapy to enable anotherCredit: Georgia Kirkos, McMaster University HAMILTON, ON, Jan. 21, 2020 -- McMaster University researchers have established in lab settings that a novel…
Better post-surgery care would dramatically improve cancer survival
Patients in low-and lower-middle-income countries were up to six times more likely to die from complications within 30 days of surgery compared with those in high-income countries, the report said. Hospitals in these countries were…
Bone density loss from Anastrozole partially reverses after treatment stops
A study by researchers from Queen Mary University of London shows that bone loss known to be associated with the use of the breast cancer prevention drug Anastrozole partially reverses, particularly at the lumbar spine, after stopping…
Sloan Kettering Institute scientists solve a 100-year-old mystery about cancer
The year 2021 marks the 100th anniversary of a fundamental discovery that's taught in every biochemistry textbook. In 1921, German physician Otto Warburg observed that cancer cells harvest energy from glucose sugar in a strangely…
Creating a safe CAR T-Cell therapy to fight solid tumors in children
Scientists at Children's Hospital Los Angeles develop newer CAR T therapy that promises to be more effective and less toxic for children with neuroblastoma Chimeric Antigen Receptor T-cell therapy--CAR T--has revolutionized leukemia…
New single-cell lineage tracing technique offers detailed insights into drivers of metastasis
A new method for tracing real-time cancer progression across thousands of cells reveals novel insights into the rates, routes and drivers of cancer metastasis. "Our work establishes that it is now possible to uniquely distinguish tens of…
Catching cancer in the act
Using CRISPR technology, Whitehead Institute Member Jonathan Weissman is tracking the lineage of individual cancer cells as they proliferate and metastasize in real timeCredit: Jeffrey Quinn/Whitehead Institute When cancer is…
Expanded PET imaging time window adds flexibility for neuroendocrine tumor patients
Credit: Images created by M. Loft et al., ENETS Neuroendocrine Tumor Center of Excellence, Rigshospitalet, Copenhagen, Denmark. Reston, Virginia--The imaging time window of 64Cu-DOTATATE positron emission tomography/computed…
Study updates breast cancer risk estimates for women with no family history
ROCHESTER, Minnesota -- A new multi-institution study led by Fergus Couch, Ph.D., a Mayo Clinic pathologist, provides more accurate estimates of breast cancer risk for U.S. women who harbor inherited mutations in breast cancer…
Dynamic, personalized treatment approach may improve outcomes in gastroesophageal cancers
The innovative phase 2 PANGEA clinical trial, with a personalized approach for treating gastroesophageal cancer, finds increased rates of survival at 1-year mark A phase 2 clinical trial providing personalized treatments based on the…
Minnesota Partnership awards 5 collaborative research grants for 2021
Minnesota Partnership for Biotechnology and Medical Genomics announced today their 2021 research awardees. This marks the partnership's 17th year of spearheading new scientific ideas from Minnesota to improve the health of, and health…
AACR and MPM announce three grants to support transformative cancer research
PHILADELPHIA, PA and CAMBRIDGE, MA - January 19, 2021 -- Three grants for research that could transform cancer therapies have been awarded by the AACR-MPM Oncology Charitable Foundation Transformative Cancer Research Grants Program,…
New, simplified genetic test effectively screens for hereditary cancers
A single test can identify the multitude of known sources of genetic variation underlying mismatch repair deficiency syndrome in inherited colon, endometrial, and other cancers, researchers report in The Journal of Molecular…
Investigational combo therapy shows benefit for TP53 mutant MDS and AML patients
Trial results show eprenetapopt plus azacitidine improves response TAMPA, Fla. -- Myelodysplastic Syndromes (MDS) and acute myeloid leukemia (AML) are rare hematologic malignancies of the bone marrow. They can occur spontaneously or…
Strange colon discovery explains racial disparities in colorectal cancer
One side of the colon ages faster than the other, scientists revealCredit: UVA Health The colons of African-Americans and people of European descent age differently, new research reveals, helping explain racial disparities in…
Study defines small-cell lung cancer subtypes and distinct therapeutic vulnerabilities for each type
Previously unknown fourth type characterized by amplified immune cell populationCredit: MD Anderson Cancer Center HOUSTON -- Researchers from The University of Texas MD Anderson Cancer Center have developed the first comprehensive…