Cancer

Bottom Line: Proton pump inhibitor (PPI) use was associated with worse outcomes in patients with urothelial cancer treated with the immunotherapeutic atezolizumab (Tecentriq), compared with patients who did not use PPIs. Journal in…

What The Study Did: Researchers in this observational study investigated the association between the number of cups of coffee consumed per day and survival in patients with advanced or metastatic colorectal cancer. Authors: Christopher…

By isolating the enzymes responsible for recycling a dangerous protein, Princeton's Yibin Kang has identified a promising new target for cancer treatmentsCredit: Photo by Maša Alečkovi "Do not erase." "Recycle me." "Free to a…

BOSTON - In a large group of patients with metastatic colorectal cancer, consumption of a few cups of coffee a day was associated with longer survival and a lower risk of the cancer worsening, researchers at Dana-Farber Cancer Institute…

What The Study Did: Changes in lung cancer treatment during the COVID-19 pandemic were evaluated in this study. Authors: Nathaniel Bouganim, M.D., of Cedars Cancer Center, McGill University Health Centre in Montreal, is the…

Newly-developed SNAP device that protects surgeons performing nasal endoscopies rolling out free to NHS after rapid design and manufactureCredit: Endoscope-i An innovative device designed to stop patients accidentally spreading…

The cover for issue 37 of Oncotarget features Figure 7, "The combination of romidepsin and KU60019 is synergistic in a xenograft model of MCL," by Scotto, et al. which reported that the antiproliferative effect induced by histone deactylase…

A study published today highlights urgent need for more interventional research in African american menCredit: Huntsman Cancer Institute Out of any other racial group, African American men have the lowest five-year survival rate…

Research from the Texas A&M College of Engineering could lead to new approaches to treating viruses and cancersCredit: Dr. Wonmuk Hwang, Texas A&M University College of Engineering Research led by Dr. Wonmuk Hwang has led…

Researchers at Queen Mary University of London, The Institute of Cancer Research, London, and the Moffitt Cancer Centre have created a mathematical model that can determine the impact of the immune system on tumour evolution. Researchers…

New approach studies psilocybin, an active ingredient in so-called "magic mushrooms" in treatment space designed for its use ROCKVILLE, Md. (September 16, 2020) - The first clinical trial to test the safety and feasibility of psilocybin…

St. Jude researchers capture the structure of PARP enzymes at work, leading to a new understanding of DNA repair that may aid cancer treatments targeting the processCredit: St. Jude Children's Research Hospital Scientists at St.…

Higher viral loads are associated with a greater risk of death among cancer and non-cancer patients hospitalized with coronavirus disease 2019 (COVID-19), researchers report September 15 in the journal Cancer Cell. Among hospitalized…

What The Study Did: Researchers investigated differences in quality of life and other outcomes (including physical functioning, body image, sexual health, anxiety and depressive symptoms) by type of breast cancer surgery (such as…

A study found a link between carotid artery calcification observable in radiographs and coronary artery disease as well as several oral infections. The calcification of the carotid artery is a sign of advanced arteriosclerosis, which may…

Researchers from the University of Tsukuba have shown how the protein Livin, an apoptosis inhibitor, enables some lymphomas to resist therapy, and that specifically targeting it may prove to be a practical treatment strategy in refractory…

Researchers compared their developed carriers for delivery of genome editing (GE) tools with other available analogues.Credit: Peter the Great St.Petersburg Polytechnic University Researchers from Peter the Great St.Petersburg…

Credit: Michigan State University Differences in biological sex can dictate lifelong disease patterns, says a new study by Michigan State University researchers that links connections between specific hormones present before and after…

Organoids made from lung cells capture cancer pathways and could be used to test treatmentsCredit: Antonella Dost, Boston Children's Hospital Lung cancer is the leading cancer killer in the U.S. It is often missed in its earlier…

PULLMAN, Wash. - Researchers in recent years have demonstrated the health benefits of soy, linking its consumption to reduced risk of cardiovascular disease, obesity, cancer and improved bone health. Now, WSU researchers are hoping to…