Cancer
More Removed Lymph Nodes Linked to Worse Outcomes After Immunotherapy in Colorectal Cancer
A retrospective study of 195 colorectal cancer patients found that removing twenty or more tumor-draining lymph nodes after neoadjuvant immunotherapy...
Engineered T Cell Receptors With Built-In ICOS Deliver Long-Lasting Anti-Tumor Power
Researchers have engineered T cell receptors fused to the co-stimulatory molecule ICOS, producing T cells that persist longer, resist exhaustion...
Scientists Flip the Drug Discovery Pipeline to Put Human Biology First in Cardiovascular Research
A new perspective argues that cardiovascular discovery should begin with integrated human multi-omics data rather than animal models, reversing the...
Receptor Occupancy Fails to Predict Immune Activation in Pembrolizumab Dosing Study
A translational modelling study finds that PD-1 receptor occupancy does not predict immune activation during pembrolizumab therapy, challenging current dosing...
Statisticians Flag Fragile Risk Model Behind Esophageal Cancer Survival Study
A new commentary warns that the three-factor risk model proposed for esophageal cancer patients achieving pathological complete response after neoadjuvant...
When the New Immune System Turns: Rare Alloimmune Disease After Childhood Bone Marrow Transplants
A UK case series documents three children who developed rare, sometimes systemic alloimmune diseases after stem cell transplants, urging earlier...
Survey Reveals Limited Financial Toxicity After Vestibular Schwannoma Treatment, Despite Employment Changes
A new survey of vestibular schwannoma patients finds widespread employment changes after treatment but only limited financial toxicity for most...
Income Protects Breast Cancer Survivors From Heart Disease Unequally, National Study Finds
A national analysis of nearly 2,800 female breast cancer survivors shows that higher income sharply reduces cardiovascular disease risk, but...
Low Muscle Mass Emerges as a Powerful Predictor of Death in Cancer Patients
A nationwide cohort study of over 635,000 South Korean cancer patients found that low muscle mass independently raised the risk...
Exercise Could Help Cancer Patients on Immunotherapy, But Nobody Is Telling Them How
A qualitative study of patients with advanced bladder and kidney cancer on immune checkpoint inhibitor therapy finds they want structured...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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