Cancer
Discovering what shapes white blood cells may enable new cancer therapies
In leukemia’s most aggressive settings, bone marrow–resident blood-cell factories fail to complete normal maturation. Instead of rapidly generating mature immune...
Advances Toward Liquid Biopsy Profiling of Antitumor Immune Responses
Tumour biopsy remains the clinical gold standard for diagnosing cancer and guiding biomarker-based treatment choices. By interrogating the tumour itself,...
Engineered Gut Bacteria Target Pancreatic Cancer in Promising Drug-Like Study
Pancreatic cancer is notoriously resistant to immunotherapy because many tumors develop an immune-suppressive, oxygen-poor “cold” microenvironment that blocks effective T...
Survival Outcomes Linked to Timing of Immune Checkpoint Inhibitor Dosing
A new analysis from a large, single-centre cohort suggests that when immune checkpoint inhibitors are given can meaningfully shape outcomes...
Randomized Phase II Trial Tests Nivolumab Then Nivolumab-Ipilimumab or Docetaxel
A new randomized Phase II clinical trial, OPTIM, is testing whether escalating immune therapy can improve outcomes for people with...
KPNA2 overexpression worsens T4 colorectal cancer prognosis by nuclear c-Myc suppression of p21
Advanced colorectal cancer remains one of oncology’s toughest challenges, especially in pathological T4 (pT4) disease where outcomes are often grim....
Blood DNA test better selects patients for prostate cancer radiopharmaceutical therapy
A simple blood test may soon help clinicians manage metastatic castration-resistant prostate cancer (mCRPC) more precisely, according to a study...
IRP1/ARID3A complex identified as a new epigenetic driver of pancreatic cancer chemoresistance
Pancreatic cancer remains among the deadliest malignancies, in part because tumors often withstand chemotherapy and later acquire resistance. In recent...
Revisiting Link Between Vegetarian Diet and Cancer Risk
A new analysis reopens one of nutrition science’s most debated questions: whether vegetarian diets change cancer risk. In a commentary...
Chinese hospital study finds smarter brain surgery boosts patient survival
Brain tumor surgery often hinges on a high-stakes trade-off: maximizing resection while protecting neurological function. Lesions near the corpus callosum...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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