Medicine

Researchers identified novel PRSS1 trypsinogen variants in IgG4-related disease tissue and linked them to M2 macrophage-driven type 2 immune responses.

New research reveals that cancer reorganizes the SUMOylation landscape in skeletal muscle and alters L3mbtl2-mediated transcriptional control, offering a molecular...

A Cell Research commentary highlights how long noncoding RNAs mediate regulatory communication between hosts and pathogens across kingdoms, reshaping infection...

A Chinese case report documents angioid streaks, an eye finding never before linked to spinocerebellar ataxia type 7, alongside striking...

A standardized osteoporosis alert sentence embedded in radiology fracture reports tripled the rate of guideline-concordant bone health care initiation within...

A prospective cohort study of 250 patients found that blood levels of interferon-gamma, IL-17, eosinophils, and IL-10 can predict the...

Reframing the global disease burden by age reveals that aging-related conditions now dominate in every income group and uniquely offer...

A six-year national cohort of 215 Chilean patients shows hantavirus cardiopulmonary syndrome still carries roughly 20 percent in-hospital mortality, heavy...

A systematic review of hepatitis B virus sequences from the Democratic Republic of Congo reveals substantial genetic diversity, marked regional...

A new umbrella review synthesizes evidence showing that opioid misuse harms children across physical health, neurodevelopment, psychosocial wellbeing, and caregiving...