About The Study: In this cohort study of 10,634 participants, childhood risk factors were found to be associated both directly and indirectly to adult cardiovascular disease (CVD), with the largest direct effect seen for body mass index (BMI) and low-density lipoprotein cholesterol. These findings suggest that intervention for childhood risk factors, in particular BMI, is warranted to reduce incidence of adult CVD as it cannot be fully mitigated by risk factor management in adulthood.
About The Study: In this cohort study of 10,634 participants, childhood risk factors were found to be associated both directly and indirectly to adult cardiovascular disease (CVD), with the largest direct effect seen for body mass index (BMI) and low-density lipoprotein cholesterol. These findings suggest that intervention for childhood risk factors, in particular BMI, is warranted to reduce incidence of adult CVD as it cannot be fully mitigated by risk factor management in adulthood.
Corresponding Author: To contact the corresponding author, Terence Dwyer, M.D., email terence.dwyer@wrh.ox.ac.uk.
To access the embargoed study: Visit our For The Media website at this link
(doi:10.1001/jamanetworkopen.2024.18148)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
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