About The Study: The combination of exercise and glucagon-like peptide-1 receptor agonist (GLP-1RA) (liraglutide) was the most effective weight loss strategy while preserving bone health in this randomized clinical trial. Liraglutide treatment alone reduced bone mineral density at clinically relevant sites more than exercise alone despite similar weight loss.
About The Study: The combination of exercise and glucagon-like peptide-1 receptor agonist (GLP-1RA) (liraglutide) was the most effective weight loss strategy while preserving bone health in this randomized clinical trial. Liraglutide treatment alone reduced bone mineral density at clinically relevant sites more than exercise alone despite similar weight loss.
Corresponding Author: To contact the corresponding author, Signe Sorensen Torekov, Ph.D., email torekov@sund.ku.dk.
To access the embargoed study: Visit our For The Media website at this link
(doi:10.1001/jamanetworkopen.2024.16775)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
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