Blood-based multi-omics guided detection of a precancerous pancreatic tumor

A new case report published in the peer-reviewed OMICS: A Journal of Integrative Biology describes how longitudinal multi-omics monitoring (LMOM) helped to detect a precancerous pancreatic tumor and led to a successful surgical intervention. Click here to read the article now. 

The patient had undergone annual blood-based LMOM, in which 143 endogenous metabolites in serum and a panel of 140 proteins in plasma were measured. David Wishart, PhD, from the University of Alberta, and coauthors, reported that three to four years after annual LMOM had begun, dramatic changes in the metabolomics and proteomics results prompted further clinical diagnostic testing for pancreatic cancer. A 2.6 cm lesion was detected in the tail of the patient’s pancreas. 

“This case report illustrates the potentials of blood LMOM for precision/personalized medicine, and new ways of thinking medical innovation for a potentially life-saving early diagnosis of pancreatic cancer,” stated the investigators.

“Longitudinal multi-omics monitoring offers promise for systems medicine and warrants translational research for early detection and clinical management of pancreatic cancer,” says Vural Özdemir, MD, PhD, DABCP, MA, Editor-in-Chief of OMICS.

About the Journal
OMICS: A Journal of Integrative Biology is an authoritative and highly innovative peer-reviewed interdisciplinary journal published monthly online, addressing the latest advances at the intersection of postgenomics medicine, biotechnology and global society, including the integration of multi-omics knowledge, data analyses and modeling, and applications of high-throughput approaches to study complex biological and societal problems. Public policy, governance and societal aspects of the large-scale biology and 21st century data-enabled sciences are also peer-reviewed. Complete tables of content and a sample issue may be viewed on the OMICS: A Journal of Integrative Biology website.

About the Journal
OMICS: A Journal of Integrative Biology is an authoritative and highly innovative peer-reviewed interdisciplinary journal published monthly online, addressing the latest advances at the intersection of postgenomics medicine, biotechnology and global society, including the integration of multi-omics knowledge, data analyses and modeling, and applications of high-throughput approaches to study complex biological and societal problems. Public policy, governance and societal aspects of the large-scale biology and 21st century data-enabled sciences are also peer-reviewed. Complete tables of content and a sample issue may be viewed on the OMICS: A Journal of Integrative Biology website.