Neural network reads cancer’s mutational fingerprints from tiny data scraps
A supervised neural network called SuRe outperforms established methods at inferring mutational signature exposures from sparse cancer sequencing data, including...
Deep learning matches expert radiologists at outlining rectal tumors on MRI
A multicenter study of 603 rectal cancer patients found that a deep learning network segmented rectal tumors on MRI with...
Leukemia drug Ponatinib shrinks hypertrophic heart cells in early lab test
A new study combining network pharmacology, molecular docking, and H9C2 cell experiments found that low-dose Ponatinib significantly reduced high-salt-induced hypertrophy...
Core Needle Biopsy Falls Short for HER2-Low Breast Cancer Classification, Study Finds
A retrospective study of 1,919 breast cancer patients in China found core needle biopsy reliably determines binary HER2 status but...
PET Scan Tumor Uptake Predicts 10-Year Survival in Early Breast Cancer
A retrospective study of 332 patients links pretreatment tumor SUVmax on PET/CT to 10-year recurrence-free and overall survival in early-stage...
Herbal pair weakens DNA repair and boosts 5-FU against colorectal cancer
A new study shows the Astragali Radix–Curcumae Rhizoma herb pair synergistically enhances 5-fluorouracil against colorectal cancer by disrupting DNA repair...
Lipid nanoparticles bring p53-targeted cancer therapy into focus
A new review argues that lipid nanoparticles, already clinically validated as mRNA carriers, could unify cancer therapy around restoring the...
Immune-cell study hints IL-1β macrophages may fuel pro-tumor signals in liver cancer
Single-cell and multi-omics analyses of hepatocellular carcinoma point to IL-1β-positive macrophages and IL-1R1-positive inflammatory fibroblasts as putative drivers of a...
Web Platform Puts Three Deep Learning Models to Work on Brain Tumor MRI Scans
A new open-access study presents a modular web platform that classifies brain tumor MRI scans in real time using a...
PYGO2 and MAML1 expression linked to early-stage papillary thyroid cancer
A study of sixty papillary thyroid carcinoma tumors found that PYGO2 and MAML1 expression levels were significantly higher in early-stage...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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