The latest volume of SLAS Discovery showcases how artificial intelligence, deep learning and data-mining strategies are accelerating drug discovery across...

Researchers have identified the first small-molecule activators of the Staphylococcus aureus ClpC/ClpP protease, mapping two druggable regulatory sites that could...

Researchers have developed TCM-Complexity, an active learning framework that uses the local structural complexity of drug–target embedding spaces to select...

Scientists co-assembled curcumin with chitosan oligosaccharides into nanoparticles that boosted the compound's water solubility about 1,100-fold and improved its gastrointestinal...

A new benchmark reveals that drug synergy prediction models often rely on memorizing historical data rather than learning generalizable pharmacological...

Researchers built a nanocrystal-loaded mucoadhesive micropatch capsule that boosts the oral bioavailability of the dandelion compound taraxasterol 3.1-fold and protects...

A controlled ablation study shows that classifier design and optimisation, not cross-attention alone, account for most of the improvement a...

A two-decade bibliometric analysis of nearly 5,000 studies maps how small molecule drug research transformed lung cancer therapy, revealing China's...

A new review in the Journal of Nanoparticle Research details how natural deep eutectic solvents integrated into nanocarriers could deliver...

A pharmacovigilance analysis of US and Japanese adverse event databases finds that PD-1 and PD-L1 checkpoint inhibitors show a robust,...