Omicron Reaches Deep Into the Niche: SARS-CoV-2 Engages Stromal Cells and Blood Stem Progenitors
A new PLOS One study shows that the Omicron variant of SARS-CoV-2 engages adipose-derived stromal cells through an NRP1-linked entry...
Arthritis Drug Turned Molecular Weapon Strikes a Rare Lung Pathogen
Chemists have converted the anti-inflammatory drug diflunisal into fluorinated biphenyl ureas that kill Mycobacterium kansasii at nanomolar-scale concentrations while leaving...
Doctors Prescribe Nature to Treat the Growing Loneliness Epidemic
A global randomized controlled trial led by the University of Colorado Boulder found that prescribing group activities like gardening and...
AI Foundation Models Show Promise for Forecasting Infectious Disease Outbreaks Across Countries
A large retrospective benchmark across six countries and more than 70 infectious diseases finds that zero-shot time series foundation models...
Five-Year Hospital Surveillance Reveals Shifting Tides in Drug-Resistant Bacteria
A five-year laboratory surveillance study at a Chinese tertiary hospital found that nearly half of clinical isolates were multidrug-resistant, but...
Rabies Vaccine Delays Endanger Bite Victims in Rural Ethiopia
A study of 260 dog bite victims in Ethiopia's Gondar zones found that 86.1 percent delayed rabies post-exposure vaccination beyond...
Typhoid Vaccine Models Reveal Optimal Schedules Depend on Local Disease Burden
A WHO-commissioned multi-model comparison finds that the optimal typhoid conjugate vaccine schedule depends on local disease incidence, case fatality risk,...
Attenuated Renewal Models Improve Epidemic Forecasts in Sexual Networks
Researchers show that renewal forecasting models attenuated by a reverse-sigmoid curve consistently outperform alternatives for predicting epidemics in overdispersed sexual...
Hospital-Acquired Infections Hit 15.7 Percent Globally as Drug-Resistant Superbugs Spread
A systematic review in BMC Infectious Diseases finds hospital-acquired infections affect 15.72 percent of patients in included studies, with the...
Tiny RNA Molecule May Explain Why Some People Resist Tuberculosis Infection
A new PLOS Pathogens study finds that the microRNA-1246 regulates macrophage lipid metabolism and helps explain why some household contacts...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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