How Metronidazole Kills Anaerobic Parasites—and How They Fight Back
A new comprehensive review details how anaerobic parasites activate the prodrug metronidazole into a DNA-damaging toxin, how the resulting oxidative...
Why Biofilms Defy Treatment and How Regulation Could Finally Catch Up
Regulatory scientists at the UK's MHRA argue that unstandardised biofilm methods and unclear evidence pathways are stalling anti-biofilm innovation, and...
Scientists Map the Gateway Protein That Helps a Devastating Tomato Virus Spread Between Plant Cells
A new study provides the first experimental evidence that the tomato brown rugose fruit virus movement protein localizes to plasmodesmata...
Plasma Cholesterol and IL-18 Flag Persistent Fatigue in HIV Patients Whose Immunity Never Recovers
A combined metabolomics and cytokine study of HIV immunological non-responders identifies elevated cholesterol and altered IL-18, IP-10, and MIF levels...
Subcutaneous Vaccination in Horses Spurs Stronger Local Reactions Than Intramuscular Shots
A randomized trial in mares found that subcutaneous injection of West Nile virus and tetanus vaccines caused significantly more swelling...
AI-designed malaria drugs could soon be grown in silkworms
Researchers propose combining AI-driven drug design with silkworm-based biomanufacturing to let malaria-endemic African nations produce their own next-generation vaccines and...
Y-Shaped Gold Nanocavities Tell Human and Mouse Noroviruses Apart by Raman Fingerprint Alone
Italian researchers have engineered a Y-shaped gold nanocavity metasurface that distinguishes human and murine noroviruses through label-free surface-enhanced Raman spectroscopy...
Why Averaged Trials Could Wrongly Condemn AI Stewardship in African Hospitals
A new opinion article argues that AI-supported antimicrobial stewardship in sub-Saharan Africa should be evaluated by which combinations of conditions...
Toward Ending HIV: Integrase Inhibitors Transform Treatment but Resistance and Inequities Persist
Two decades of relentless pharmacological innovation have transformed HIV from a uniformly fatal diagnosis into a manageable chronic infection for...
Viruses From Sewage Turn Bone Cement Into a Weapon Against MRSA Implant Infections
Researchers isolated six MRSA-killing bacteriophages from Indian waterways and hospital sewage and showed that combining them with nano-layered double hydroxide-modified...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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