Immunogenicity and Safety of BNT162b2 in Juvenile Immune-Mediated Inflammatory Disease Patients
A new phase of COVID-19 vaccine evaluation is underway for a group often underrepresented in clinical trials: children and adolescents...
All-Trans Retinoic Acid Suppresses Severe Fever With Thrombocytopenia Virus Inflammation in Mice
Severe fever with thrombocytopenia syndrome (SFTS), driven by SFTS virus, can trigger life-threatening systemic inflammation, yet targeted host-directed therapies have...
CCHFV Polymerase Enables RNA Synthesis and Shows Substrate Analog Inhibition
Viral polymerases of the Nairoviridae family are unusually large, and until now their atomic details have remained largely unexplored. In...
Infection Study Maps Protein Contact Sites, Shows Influenza Hijacks Paraspeckles
Influenza A virus is infamous for its speed—yet the molecular choreography inside infected cells is still being uncovered. In a...
Microbe Lactic Acid Weakens Interferon by Blocking Antiviral Signaling
A study in Nature Communications reports that lactic acid produced by host cells can blunt the antiviral power of interferons...
Klebsiella pneumoniae Suppresses Blood Vessel Dilation via Capsule and T6SS
A new study suggests that Klebsiella pneumoniae can actively blunt the body’s normal blood-vessel relaxation, a key step in inflammation...
Scientists uncover molecular mechanisms of Pirsonia diadema infection in diatoms
Marine blooms that color coastal waters may be reshaped not only by sunlight and nutrients, but also by microscopic parasites....
Genome-wide screen finds host-targeted drugs and SARS-CoV-2 pro-viral pathways
A new study published in npj Viruses reports that a genome-wide host-directed screening strategy can uncover both antiviral drug candidates...
GHP-88310 blocks airborne and contact transmission in ferret measles model
A new antiviral candidate, GHP-88310, shows strong promise for preventing measles-like disease transmission in a ferret model, according to a...
Republican push fuels rapid rise of antivaccine laws in US states
A new analysis led by Boston University School of Public Health researchers finds that anti-vaccine attitudes, once largely expressed as...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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