New research reveals that the deubiquitinase USP22 protects bone marrow stem cells from oxidative stress-induced senescence by stabilizing the transcription...

A biochemical survey of the annual killifish Nothobranchius guentheri shows that 24 of 27 clinical chemistry markers decline with age,...

A 12-week resistance training study in healthy older adults found that functional performance improved consistently while pain, quality of life,...

Researchers have developed and validated the first population-based prediction equations that estimate appendicular skeletal muscle mass in Asian adults using...

A randomised controlled trial has investigated whether unconditional cash transfers can alter epigenetic measures of ageing and cognitive development in...

A comprehensive new review details how senescent fibroblasts, macrophages, keratinocytes and stem cells drive skin aging through ROS, DNA damage,...

Researchers have identified the little-studied transmembrane protein PTCHD4 as a novel regulator of cellular senescence whose deletion extends lifespan and...

A new review in Biogerontology argues that senescent cells and their inflammatory secretions act as a convergent, independently targetable driver...

A large longitudinal study of Chinese adults finds that persistent handgrip strength asymmetry and any abnormal two-wave pattern of low...

A new GeroScience review proposes that B cell-intrinsic aging relaxes immune tolerance while chronic inflammaging selectively expands autoreactive B cell...