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Does inflammation in mid-life affect late-life mobility?

June 12, 2024
in Medicine
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In a recent study published in the Journal of the American Geriatric Society, having high inflammation in mid-life was associated with a clinically meaningful slower gait speed—an indicator of mobility—20 years later.

In a recent study published in the Journal of the American Geriatric Society, having high inflammation in mid-life was associated with a clinically meaningful slower gait speed—an indicator of mobility—20 years later.

In the study, which included 4,758 community-dwelling adults, the link between high inflammation and slower late-life gait speed was especially strong for people with sustained high inflammation over the 20-plus years of follow-up. The association was evident even among the healthiest adults who never experienced other common conditions such as obesity, hypertension, or diabetes.

“These findings suggest that monitoring inflammation has the potential to be important for late life health, similar to monitoring routine health metrics such as blood pressure and glucose,” said corresponding author B. Gwen Windham, MD, MHS.

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Additional Information
NOTE: 
The information contained in this release is protected by copyright. Please include journal attribution in all coverage. For more information or to obtain a PDF of any study, please contact: Sara Henning-Stout, newsroom@wiley.com.

About the Journal
Journal of the American Geriatric Society is the go-to journal for clinical aging research. We provide a diverse, interprofessional community of healthcare professionals with the latest insights on geriatrics education, clinical practice, and public policy—all supporting the high-quality, person-centered care essential to our well-being as we age.

About Wiley
Wiley is a knowledge company and a global leader in research, publishing, and knowledge solutions. Dedicated to the creation and application of knowledge, Wiley serves the world’s researchers, learners, innovators, and leaders, helping them achieve their goals and solve the world’s most important challenges. For more than two centuries, Wiley has been delivering on its timeless mission to unlock human potential. Visit us at Wiley.com. Follow us on Facebook, Twitter, LinkedIn and Instagram.



Journal

Journal of the American Geriatrics Society

DOI

10.1111/jgs.18978

Article Title

Associations of mid-to-late-life inflammation with late-life mobility and the influences of chronic comorbidities, race, and social determinants of health: The Atherosclerosis Risk in Communities Study

Article Publication Date

12-Jun-2024

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