Tag: vaccine design

Australian researchers have completed the first head-to-head comparison of three mRNA-lipid nanoparticle vaccine platforms in human blood, revealing key differences ...

Cryo-electron microscopy of porcine neutralizing antibodies bound to foot-and-mouth disease virus reveals how mutations on VP1 and VP3 drive antigenic ...

A computational reverse vaccinology study has designed BAFF- and APRIL-adjuvanted multi-epitope vaccine candidates against human metapneumovirus, a major respiratory pathogen ...

New structural and biochemical analyses of the hepatitis C virus E2 glycoprotein show that germline-reverted broadly neutralizing antibodies recognize the ...

A coupled epidemiological and evolutionary model of influenza shows that vaccination can accelerate viral escape and even raise infection incidence ...

A new critical review argues that artificial intelligence has accelerated epitope prediction for multi-epitope vaccines, but chemical developability, nanocarrier formulation ...

Researchers have mapped conserved epitopes on the sarbecovirus spike protein that allow three monoclonal antibodies to neutralize a wide range ...

New phylogenomic analysis reveals that three ECSA sub-lineages of chikungunya virus each evolved distinct mosquito-adaptation strategies, explaining their regional dominance ...

A new cryo-EM and biophysical study shows that removing the N153 glycan from dengue virus 2 exposes previously hidden epitopes, ...

New research shows that bacterial proteins injected into gut epithelial cells, rather than those left on the bacterial surface, program ...