TP53 Mutations Linked to Poor Prognosis in DLBCL
In the realm of hematological malignancies, diffuse large B-cell lymphoma (DLBCL) represents a formidable challenge due to its heterogeneous nature ...
Tag: TP53 gene mutations
Bayesian Method Enhances TP53 Variant Classification for Li-Fraumeni
In a groundbreaking development, researchers have unveiled a novel and robust methodology for gene-specific variant classification that could significantly enhance ...
Boosting Cancer Mutant p53 Y220C with Indazoles
In a groundbreaking study poised to reshape the future of cancer therapeutics, researchers have unveiled a novel approach to reactivating ...
Sex and Smoking Shape Bladder Mutation Patterns
A groundbreaking advance in cancer genomics has emerged from the ultradeep sequencing of normal human tissues, revealing a natural saturation ...
TP53 Variants Identify Osteosarcoma-Prone Carriers
The gene TP53, often referred to as the “guardian of the genome,” has long fascinated scientists because of its critical ...
New Triazole-Oxazole Hybrids Target p53–MDM2 Pathway
In the ongoing battle against cancer, researchers have made significant strides in developing targeted therapies that can improve treatment outcomes ...
New p53 Targets Uncovered by Researchers to Enhance Cancer Treatment Strategies
A new groundbreaking study has emerged from researchers at the Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins University School ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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